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Alain Trouve

Explore the profile of Alain Trouve including associated specialties, affiliations and a list of published articles. Areas
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Articles 37
Citations 656
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Recent Articles
1.
Stouffer K, Chen X, Zeng H, Charlier B, Younes L, Trouve A, et al.
bioRxiv . 2024 Nov; PMID: 39574713
Advancements in imaging and molecular techniques enable the collection of subcellular-scale data. Diversity in measured features, resolution, and physical scope of capture across technologies and experimental protocols pose numerous challenges...
2.
Marchitelli R, Martinot M, Trouve A, Banaschewski T, Bokde A, Desrivieres S, et al.
Mol Psychiatry . 2024 Jul; 29(12):3769-3778. PMID: 38956372
Perseverative negative thoughts, known as rumination, might arise from emotional challenges and preclude mental health when transitioning into adulthood. Due to its multifaceted nature, rumination can take several ruminative response...
3.
Stouffer K, Trouve A, Younes L, Kunst M, Ng L, Zeng H, et al.
Nat Commun . 2024 Apr; 15(1):3530. PMID: 38664422
This paper explicates a solution to building correspondences between molecular-scale transcriptomics and tissue-scale atlases. This problem arises in atlas construction and cross-specimen/technology alignment where specimens per emerging technology remain sparse...
4.
Miller M, Trouve A, Younes L
Med Image Anal . 2024 Jan; 93:103068. PMID: 38176357
Advances in the development of largely automated microscopy methods such as MERFISH for imaging cellular structures in mouse brains are providing spatial detection of micron resolution gene expression. While there...
5.
Miller M, Tward D, Trouve A
BME Front . 2023 May; 2022. PMID: 37206893
Objective: The objective of this research is to unify the molecular representations of spatial transcriptomics and cellular scale histology with the tissue scales of computational anatomy for brain mapping. Impact...
6.
Ledoux J, Stolyarchuk M, Bachelier E, Trouve A, Tchertanov L
Int J Mol Sci . 2022 Apr; 23(7). PMID: 35409257
Human vitamin K epoxide reductase (hVKORC1) enzymatic activity requires an initial activation by a specific redox protein, a less studied step in the hVKORC1 vital cycle. Significant steric conditions must...
7.
Ledoux J, Trouve A, Tchertanov L
Int J Mol Sci . 2022 Feb; 23(3). PMID: 35163518
RTK KIT regulates a variety of crucial cellular processes via its cytoplasmic domain (CD), which is composed of the tyrosine kinase domain, crowned by the highly flexible domains-the juxtamembrane region,...
8.
Ledoux J, Trouve A, Tchertanov L
Int J Mol Sci . 2021 Jul; 22(14). PMID: 34298994
The kinase insert domain (KID) of RTK KIT is the key recruitment region for downstream signalling proteins. KID, studied by molecular dynamics simulations as a cleaved polypeptide and as a...
9.
Nicolai A, Limnios M, Trouve A, Audiffren J
IEEE Trans Neural Syst Rehabil Eng . 2021 Feb; 29:478-487. PMID: 33539301
Falls are a major concern of public health, particularly for older adults, as the consequences of falls include serious injuries and death. Therefore, the understanding and evaluation of postural control...
10.
Stolyarchuk M, Ledoux J, Maignant E, Trouve A, Tchertanov L
Int J Mol Sci . 2021 Jan; 22(2). PMID: 33466919
Redox (reduction-oxidation) reactions control many important biological processes in all organisms, both prokaryotes and eukaryotes. This reaction is usually accomplished by canonical disulphide-based pathways involving a donor enzyme that reduces...