» Authors » Alain Roussel

Alain Roussel

Explore the profile of Alain Roussel including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 80
Citations 2232
Followers 0
Related Specialties
Top 10 Co-Authors
Published In
Affiliations
Soon will be listed here.
Recent Articles
1.
Bessonne M, Morel J, Nevers Q, Da Costa B, Ballandras-Colas A, Chenavier F, et al.
PLoS Pathog . 2024 Jun; 20(6):e1011642. PMID: 38875296
Influenza viruses transcribe and replicate their genome in the nucleus of the infected cells, two functions that are supported by the viral RNA-dependent RNA-polymerase (FluPol). FluPol displays structural flexibility related...
2.
Zammit M, Bartoli J, Kellenberger C, Melani P, Roussel A, Cascales E, et al.
Sci Rep . 2024 Mar; 14(1):6577. PMID: 38503809
The type IX secretion system (T9SS) is a large multi-protein transenvelope complex distributed into the Bacteroidetes phylum and responsible for the secretion of proteins involved in pathogenesis, carbohydrate utilization or...
3.
Le T, Kellenberger C, Boyer M, Santucci P, Flaugnatti N, Cascales E, et al.
Int J Mol Sci . 2023 Jan; 24(2). PMID: 36675258
The type VI secretion system (T6SS) delivers enzymatic effectors into target cells to destroy them. Cells of the same strain protect themselves against effectors with immunity proteins that specifically inhibit...
4.
Thebault S, Lejal N, Dogliani A, Donchet A, Urvoas A, Valerio-Lepiniec M, et al.
PLoS Pathog . 2022 Sep; 18(9):e1010799. PMID: 36067253
The binding of the SARS-CoV-2 spike to angiotensin-converting enzyme 2 (ACE2) promotes virus entry into the cell. Targeting this interaction represents a promising strategy to generate antivirals. By screening a...
5.
Goulet A, Cambillau C, Roussel A, Imbert I
Viruses . 2022 Jul; 14(7). PMID: 35891516
Hepatitis E virus (HEV) is a major cause of acute viral hepatitis in humans globally. Considered for a long while a public health issue only in developing countries, the HEV...
6.
Pagneux Q, Roussel A, Saada H, Cambillau C, Amigues B, Delauzun V, et al.
Commun Med (Lond) . 2022 May; 2:56. PMID: 35619829
Background: An ongoing need during the COVID-19 pandemic has been the requirement for accurate and efficient point-of-care testing platforms to distinguish infected from non-infected people, and to differentiate SARS-CoV-2 infections...
7.
Fuchsbauer O, Lunar Silva I, Cascales E, Roussel A, Leone P
J Biol Chem . 2022 Jan; 298(3):101618. PMID: 35065963
Porphyromonas gingivalis, the major human pathogen bacterium associated with periodontal diseases, secretes virulence factors through the Bacteroidetes-specific type IX secretion system (T9SS). Effector proteins of the T9SS are recognized by...
8.
Nguyen V, Spinelli S, Cascales E, Roussel A, Cambillau C, Leone P
PLoS One . 2021 Jul; 16(7):e0254232. PMID: 34214145
The type VI secretion system (T6SS) is a widespread mechanism of protein delivery into target cells, present in more than a quarter of all sequenced Gram-negative bacteria. The T6SS constitutes...
9.
Amigues B, Zhu J, Gaubert A, Arena S, Renzone G, Leone P, et al.
Sci Rep . 2021 Jun; 11(1):13172. PMID: 34162975
Odorant-binding proteins (OBPs), as they occur in insects, form a distinct class of proteins that apparently has no closely related representatives in other animals. However, ticks, mites, spiders and millipedes...
10.
Trinh T, Gaubert A, Melani P, Cambillau C, Roussel A, Leone P
Acta Crystallogr F Struct Biol Commun . 2021 Jun; 77(Pt 6):171-176. PMID: 34100775
GldL is an inner-membrane protein that is essential for the function of the type IX secretion system (T9SS) in Flavobacterium johnsoniae. The complex that it forms with GldM is supposed...