Alaaeldin Saleh
Overview
Explore the profile of Alaaeldin Saleh including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
115
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Recent Articles
1.
Idoudi S, Saleh A, Akkbik M, Amine L, Alansari K, Rachid O, et al.
Pharmaceutics
. 2025 Jan;
16(12.
PMID: 39771482
Ketamine HCl, an FDA-approved therapeutic, is administered through various routes, including intranasal delivery. Administering an adequate therapeutic dose of intranasal ketamine HCl is challenging due to the limited volume that...
2.
Daas S, Thanassoulas A, Calver B, Saleh A, Abdelrahman D, Hasan W, et al.
J Cell Biochem
. 2024 Jul;
125(8):e30619.
PMID: 38946237
Calmodulin (CaM) is a ubiquitous, small cytosolic calcium (Ca)-binding sensor that plays a vital role in many cellular processes by binding and regulating the activity of over 300 protein targets....
3.
Saleh A, Thanassoulas A, Aliyev E, Swann K, Naija A, Yalcin H, et al.
Biomedicines
. 2024 Jun;
12(6).
PMID: 38927390
The sperm-specific phospholipase C zeta (PLCζ) protein is widely considered as the predominant physiological stimulus for initiating the Ca release responsible for oocyte activation during mammalian fertilization. The increasing number...
4.
Saleh A, Kashir J, Thanassoulas A, Safieh-Garabedian B, Lai F, Nomikos M
Front Cell Dev Biol
. 2020 Feb;
8:28.
PMID: 32064262
Sperm-specific phospholipase C zeta (PLCζ) is widely considered to be the physiological stimulus responsible for generating calcium (Ca) oscillations that induce egg activation and early embryonic development during mammalian fertilization....
5.
Daas S, Thanassoulas A, Calver B, Beck K, Salem R, Saleh A, et al.
Ann N Y Acad Sci
. 2019 Apr;
1448(1):19-29.
PMID: 30937913
Calmodulin (CaM) is a universal calcium (Ca )-binding messenger that regulates many vital cellular events. In cardiac muscle, CaM associates with ryanodine receptor 2 (RyR2) and regulates excitation-contraction coupling. Mutations...
6.
Daas S, Fakhro K, Thanassoulas A, Krishnamoorthy N, Saleh A, Calver B, et al.
Biochem J
. 2018 Nov;
475(24):3933-3948.
PMID: 30446606
The most common inherited cardiac disorder, hypertrophic cardiomyopathy (HCM), is characterized by thickening of heart muscle, for which genetic mutations in cardiac myosin-binding protein C3 () gene, is the leading...
7.
Hasasna H, Saleh A, Al Samri H, Athamneh K, Attoub S, Arafat K, et al.
Sci Rep
. 2016 Feb;
6:21144.
PMID: 26888313
Recently, we reported that Rhus coriaria exhibits anticancer activities by promoting cell cycle arrest and autophagic cell death of the metastatic triple negative MDA-MB-231 breast cancer cells. Here, we investigated...
8.
Dhaheri Y, Attoub S, Arafat K, AbuQamar S, Viallet J, Saleh A, et al.
PLoS One
. 2013 Jul;
8(7):e68808.
PMID: 23874773
Background: We have recently reported that Origanummajorana exhibits anticancer activity by promoting cell cycle arrest and apoptosis of the metastatic MDA-MB-231 breast cancer cell line. Here, we extended our study...