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Alaa M Hammad

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Articles 44
Citations 243
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Recent Articles
11.
Ikhmais B, Hammad A, Abusara O, Hamadneh L, Abumansour H, Abdallah Q, et al.
Curr Issues Mol Biol . 2023 Oct; 45(10):7996-8012. PMID: 37886948
Repurposing existing drugs appears to be a potential solution for addressing the challenges in the treatment of non-small cell lung cancer (NSCLC). β-adrenoceptor antagonist drugs (β-blockers) have tumor-inhibiting effects, making...
12.
Hamed R, Abu Alata W, Abu-Sini M, Abulebdah D, Hammad A, Aburayya R
Gels . 2023 Jul; 9(7). PMID: 37504471
Nanoemulsions and bigels are biphasic delivery systems that can be used for topical applications. The aim of this study was to incorporate an oil-in-water ciprofloxacin hydrochloride nanoemulsion (CIP.HCl NE) into...
13.
Salem Y, Rajha H, Sunoqrot S, Hammad A, Castangia I, Manconi M, et al.
Molecules . 2023 Jul; 28(13). PMID: 37446711
Grape seed of Obeidi, a white Lebanese autochthonous variety, was previously tested in different studies as a valuable source of bioactive molecules such as polyphenols, oils, and proteins by means...
14.
Sunoqrot S, Alkurdi M, Al Bawab A, Hammad A, Tayyem R, Abu Obeed A, et al.
Saudi Pharm J . 2023 May; 31(6):845-853. PMID: 37228320
Morin (3,5,7,2',4'-pentahydroxyflavone; MR) is a bioactive plant polyphenol whose therapeutic efficacy is hindered by its poor biopharmaceutical properties. The purpose of this study was to develop a nanoparticle (NP) formulation...
15.
Hammad A, Shawaqfeh B, Hikmat S, Al-Qirim T, Hamadneh L, Al-Kouz S, et al.
Toxics . 2023 Apr; 11(4). PMID: 37112594
Paracetamol (acetaminophen, APAP) is the most common non-prescription analgesic drug used during pregnancy. The aim of this study was to investigate the effect of vitamin E on acute APAP toxicity...
16.
Hammad A, Alhusban A, Alzaghari L, Alasmari F, Sari Y
Metabolites . 2023 Apr; 13(4). PMID: 37110173
Cigarette smoke withdrawal can cause anxiety-like behavior and modulate neurotransmitter-related proteins in the brain. We examined the effects of cigarette smoke with and without aspirin treatment on the concentrations of...
17.
Amawi H, Arabyat R, Al-Azzam S, AlZubi T, Uwais H, Hammad A, et al.
Medicina (Kaunas) . 2023 Apr; 59(4). PMID: 37109685
: Venous thromboembolism is one of the leading causes of mortality and disability worldwide. Treatment with anticoagulation therapy is essential and requires a delicate approach to select the most appropriate...
18.
Hammad A, Alzaghari L, Alfaraj M, Al-Shawaf L, Sunoqrot S
Drug Deliv Transl Res . 2023 Apr; 13(7):1967-1982. PMID: 37069327
Antioxidant-rich plant extracts have demonstrated tremendous value as inflammatory modulators and as nanomaterial precursors. Chronic cigarette smoking alters neurotransmitter systems, particularly the glutamatergic system, and produces neuroinflammation. This study aimed...
19.
Abusara O, Ibrahim A, Issa H, Hammad A, Ismail W
Curr Issues Mol Biol . 2023 Mar; 45(3):2170-2181. PMID: 36975509
Aldehyde dehydrogenase (ALDH) enzymes are involved in the growth and development of several tissues, including cancer cells. It has been reported that targeting the ALDH family, including the ALDH1A subfamily,...
20.
Hammad A, Alzaghari L, Alfaraj M, Al-Qerem W, Talib W, Alasmari F, et al.
Front Pharmacol . 2023 Jan; 13:1047236. PMID: 36699078
Chronic exposure to cigarette smoke produces neuroinflammation and long-term changes in neurotransmitter systems, especially glutamatergic systems. We examined the effects of cigarette smoke on astroglial glutamate transporters as well as...