Akshay Desai
Overview
Explore the profile of Akshay Desai including associated specialties, affiliations and a list of published articles.
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Articles
36
Citations
885
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Recent Articles
21.
Pradhan M, Desai A, Palakal M
BMC Syst Biol
. 2013 Dec;
7:141.
PMID: 24369052
Background: Epigenetics refers to the reversible functional modifications of the genome that do not correlate to changes in the DNA sequence. The aim of this study is to understand DNA...
22.
Cheng S, Lam C, Shah A, Claggett B, Desai A, Hilkert R, et al.
J Hypertens
. 2013 Dec;
32(1):174-80.
PMID: 24309488
Objective: Diastolic dysfunction is associated with adverse outcomes and is highly prevalent among older adults with hypertension. Lowering SBP with antihypertensive therapy has been shown to improve diastolic function, but...
23.
OMeara E, de Denus S, Rouleau J, Desai A
Curr Heart Fail Rep
. 2013 Oct;
10(4):350-8.
PMID: 24122286
Patients with heart failure with preserved ejection fraction (HF-PEF) comprise a growing proportion of the overall HF burden. The pathophysiology of HF-PEF is complex, and relates to the interplay between...
24.
Vardeny O, Wu D, Desai A, Rossignol P, Zannad F, Pitt B, et al.
J Am Coll Cardiol
. 2012 Oct;
60(20):2082-9.
PMID: 23083787
Objectives: This study investigated the influence of baseline and worsening renal function (WRF) on the efficacy of spironolactone in patients with severe heart failure (HF). Background: Renal dysfunction or decline...
25.
Pouleur A, Uno H, Prescott M, Desai A, Appelbaum E, Lukashevich V, et al.
J Renin Angiotensin Aldosterone Syst
. 2011 Jul;
12(4):483-90.
PMID: 21746765
Background: High circulating aldosterone levels stimulate myocardial fibrosis and left ventricular hypertrophy (LVH). However, it is not clear whether suppression of aldosterone directly contributes to LVH regression in hypertensive patients....
26.
Solomon S, Shin S, Shah A, Skali H, Desai A, Kober L, et al.
Eur Heart J
. 2011 Feb;
32(10):1227-34.
PMID: 21317148
Aims: Direct renin inhibitors provide an alternative approach to inhibiting the renin-angiotensin-aldosterone system (RAAS) at the most proximal, specific, and rate-limiting step. We tested the hypothesis that direct renin inhibition...
27.
Resnic F, Desai A
J Thorac Cardiovasc Surg
. 2010 Jul;
140(1):257-9.
PMID: 20620388
No abstract available.
28.
Desai A, Lewis E, Solomon S, McMurray J, Pfeffer M
Eur J Heart Fail
. 2010 Jun;
12(9):936-42.
PMID: 20525985
Aims: Randomized clinical trials have suggested that treatment of anaemia with erythropoiesis-stimulating agents (ESAs) in patients with cancer or chronic kidney disease may increase cardiovascular risk. We therefore examined the...
29.
Solomon S, Verma A, Desai A, Hassanein A, Izzo J, Oparil S, et al.
Hypertension
. 2009 Dec;
55(2):241-8.
PMID: 19996069
Diastolic dysfunction may precede development of heart failure in hypertensive patients. We randomized 228 patients with uncontrolled hypertension, preserved ejection fraction, and diastolic dysfunction to 2 targeted treatment strategies: intensive,...
30.
Buckley O, Doyle L, Padera R, Lakdawala N, Dorbala S, Di Carli M, et al.
J Nucl Cardiol
. 2009 Sep;
17(2):328-32.
PMID: 19777320
No abstract available.