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Akito Hata

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Articles 133
Citations 1363
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Recent Articles
1.
Tanzawa S, Yoshioka H, Misumi T, Miyauchi E, Ninomiya K, Murata Y, et al.
Ther Adv Med Oncol . 2025 Feb; 17:17588359251318850. PMID: 39957806
Background: The clinical impact of hypomagnesemia induced by necitumumab plus gemcitabine and cisplatin (GCN) as a second-line or later therapy is unclear. Objective: We aimed to evaluate the clinical characteristics...
2.
Fujimoto D, Shibaki R, Kimura K, Haratani K, Tamiya M, Kijima T, et al.
Lung Cancer . 2025 Jan; 199:108079. PMID: 39787635
Objectives: The lack of definitive biomarkers presents a significant challenge for chemo-immunotherapy in extensive-stage small-cell lung cancer (ES-SCLC). We aimed to identify key genes associated with chemo-immunotherapy efficacy in ES-SCLC...
3.
Sugisaka J, Fujimoto D, Tamiya M, Hata A, Matsumoto H, Yokoyama T, et al.
Lung Cancer . 2024 Dec; 199:108056. PMID: 39674045
Background: Chemoimmunotherapy is the standard first-line treatment for extensive-stage small-cell lung cancer (ES-SCLC); however, its real-world long-term outcomes associated with patient backgrounds are still unclear. We explored this association using...
4.
Hata A, Katakami N, Takase N, Kibata K, Yamanaka Y, Tamiya M, et al.
Lung Cancer . 2024 Oct; 197:107988. PMID: 39393258
Introduction: Many clinical studies showed a synergy of epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKIs) and vascular endothelial growth factor inhibitors. We hypothesized afatinib plus bevacizumab exerts clinical potency...
5.
Shibaki R, Fujimoto D, Miyauchi E, Tsukita Y, Nakachi I, Arai D, et al.
Lung Cancer . 2024 Sep; 196:107958. PMID: 39312871
Objectives: Certain guidelines recommend caution when administering immunotherapy in patients with pre-existing interstitial lung disease (ILD) owing to the high incidence of pneumonitis induced by anti-cancer therapy. A prospective clinical...
6.
Yagishita S, Goto Y, Nishio M, Akamatsu H, Hayashi H, Miura S, et al.
JTO Clin Res Rep . 2024 Aug; 5(7):100683. PMID: 39091595
Introduction: This study validated real-world pharmacokinetic (PK) data using an established population PK (PopPK) model for atezolizumab in Japanese patients with NSCLC and explored the relationship between PK parameters, effectiveness,...
7.
Hata A, Iwasawa S, Sasaki Y, Tajima K, Chiba Y
Adv Ther . 2024 Jul; 41(9):3520-3538. PMID: 38990434
Introduction: Atezolizumab, bevacizumab, carboplatin, and paclitaxel (ABCP) combination therapy is a standard of care for advanced non-squamous non-small cell lung cancer (NSQ-NSCLC); however, the lack of safety data limits its...
8.
Kariya M, Yamamoto K, Kawamura A, Tanizaki S, Ueda K, Sai K, et al.
Support Care Cancer . 2024 Jun; 32(6):400. PMID: 38829486
Purpose: Although several potential radioprotectants have been explored, radiation esophagitis is still difficult to control. Further development of supportive therapies is required. Our purpose was to investigate the efficacy and...
9.
Azad T, Nanjo S, Jin M, Chabon J, Kurtz D, Chaudhuri A, et al.
NPJ Precis Oncol . 2024 May; 8(1):121. PMID: 38806586
Cerebrospinal fluid tumor-derived DNA (CSF-tDNA) analysis is a promising approach for monitoring the neoplastic processes of the central nervous system. We applied a lung cancer-specific sequencing panel (CAPP-Seq) to 81...
10.
Kachi S, Sumitomo S, Oka H, Hata A, Ohmura K
Front Immunol . 2024 May; 15:1400097. PMID: 38799449
This report describes the case of a 48-year-old woman who presented with sternoclavicular joint arthritis after administration of an immune checkpoint inhibitor (ICI), durvalumab, for small cell lung carcinoma. The...