Akira Sekikawa
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Explore the profile of Akira Sekikawa including associated specialties, affiliations and a list of published articles.
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151
Citations
2746
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Recent Articles
11.
Zhang X, Fujiyoshi A, Ahuja V, Vishnu A, Barinas-Mitchell E, Kadota A, et al.
Int J Cardiol
. 2022 Feb;
352:158-164.
PMID: 35122909
Background: Equol, an isoflavone (ISF)-derived metabolite by the gut microbiome in certain individuals termed as equol-producers, might be the key anti-atherogenic component of ISFs. Our objective was to determine the...
12.
Zhang X, Veliky C, Birru R, Barinas-Mitchell E, Magnani J, Sekikawa A
Nutrients
. 2021 Nov;
13(11).
PMID: 34835997
Equol, a soy isoflavone-derived metabolite of the gut microbiome, may be the key cardioprotective component of soy isoflavones. Systematic reviews have reported that soy isoflavones have no to very small...
13.
Cui C, Higashiyama A, Lopresti B, Ihara M, Aizenstein H, Watanabe M, et al.
Brain Sci
. 2021 Sep;
11(9).
PMID: 34573201
The Alzheimer's Disease Neuroimaging Initiative showed that Japanese had significantly lower brain Aβ burden than Americans among a cognitively normal population. This cross-sectional study aimed to compare vascular disease burden,...
14.
Marron M, Moore S, Wendell S, Boudreau R, Miljkovic I, Sekikawa A, et al.
Geroscience
. 2021 May;
44(2):1083-1094.
PMID: 33991295
Apolipoprotein E (APOE) allelic variation is associated with differences in overall circulating lipids and risks of major health outcomes. Lipid profiling provides the opportunity for a more detailed description of...
15.
Sullivan K, Ran X, Wu F, Chang C, Sharma R, Jacobsen E, et al.
J Am Geriatr Soc
. 2021 Apr;
69(8):2185-2194.
PMID: 33904156
Background/objective: Poor air quality is implicated as a risk factor for cognitive impairment and dementia. Few studies have examined these associations longitudinally in well-characterized population-based cohorts with standardized annual assessment...
16.
Zaid M, Fujiyoshi A, Hisamatsu T, Kadota A, Kadowaki S, Satoh A, et al.
J Atheroscler Thromb
. 2021 Feb;
29(2):282-295.
PMID: 33551394
Aims: The utility of carotid intima-media thickness (cIMT) as a marker for coronary heart disease is under heavy debate. This is predominantly due to the lack of a standard definition...
17.
Sekikawa A, Higashiyama A, Lopresti B, Ihara M, Aizenstein H, Watanabe M, et al.
Alzheimers Dement (N Y)
. 2020 Oct;
6(1):e12089.
PMID: 33117881
Introduction: Equol, a metabolite of a soy isoflavone transformed by the gut microbiome, is anti-oxidant and anti-amyloidogenic. We assessed the associations of equol with white matter lesion normalized to total...
18.
Nakama C, Kadowaki T, Choo J, El-Saed A, Kadota A, Willcox B, et al.
Int J Cardiol Heart Vasc
. 2020 Sep;
30:100618.
PMID: 32904231
Introduction: Inverse associations of cardiovascular disease (CVD) and atherosclerosis with osteoporosis and bone mineral density (BMD) have been reported in post-menopausal women and elderly men. We aimed to investigate an...
19.
Cui C, Mackey R, Shaaban C, Kuller L, Lopez O, Sekikawa A
Alzheimers Dement
. 2020 Aug;
16(10):1402-1411.
PMID: 32803916
Introduction: A body of literature reported associations between late-life general adiposity measures (eg, body mass index) and dementia. Little is known about the association of late-life body composition with dementia...
20.
Man B, Cui C, Zhang X, Sugiyama D, Barinas-Mitchell E, Sekikawa A
Eur J Nutr
. 2020 Jun;
60(2):603-614.
PMID: 32529287
Purpose: Some but not all randomized controlled trials (RCTs) of soy isoflavones showed their beneficial effect on arterial stiffness, a predictor of cardiovascular events, dementia, and all-cause mortality, independent of...