Akira Nifuji
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Explore the profile of Akira Nifuji including associated specialties, affiliations and a list of published articles.
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49
Citations
985
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Recent Articles
11.
Shimada A, Ideno H, Arai Y, Komatsu K, Wada S, Yamashita T, et al.
J Bone Miner Res
. 2018 Apr;
33(8):1532-1543.
PMID: 29694681
Little is known about the molecular mechanisms of enthesis formation in mature animals. Here, we report that annexin A5 (Anxa5) plays a critical role in the regulation of bone ridge...
12.
Kamiunten T, Ideno H, Shimada A, Arai Y, Terashima T, Tomooka Y, et al.
Exp Cell Res
. 2017 May;
357(2):202-210.
PMID: 28527696
Teeth develop through interactions between epithelial and mesenchymal tissues mediated by a signaling network comprised of growth factors and transcription factors. However, little is known about how epigenetic modifiers affect...
13.
Huynh N, Everts V, Nifuji A, Pavasant P, Ampornaramveth R
Bone
. 2016 Nov;
95:76-84.
PMID: 27871909
Methods: RUNX2 protein and its acetylation was analyzed by immunoprecipitation and western blotting. The effect of TSA on osteogenic differentiation of hPDLCs was investigated using in vitro 3D cultures. hPDLCs...
14.
Kawasaki M, Izu Y, Hayata T, Ideno H, Nifuji A, Sheffield V, et al.
Bone
. 2016 May;
101:179-190.
PMID: 27170093
Bardet-Biedl Syndrome (BBS) is an autosomal recessive disorder and is classified as one of the ciliopathy. The patients manifest a characteristic craniofacial dysmorphology but the effects of Bbs3 deficiency in...
15.
Pawaputanon Na Mahasarakham C, Ezura Y, Kawasaki M, Smriti A, Moriya S, Yamada T, et al.
J Cell Physiol
. 2015 Sep;
231(4):887-95.
PMID: 26332449
Osteoporosis is one of the most prevalent diseases and the number of patients suffering from this disease is soaring due to the increase in the aged population in the world....
16.
Wada S, Ideno H, Shimada A, Kamiunten T, Nakamura Y, Nakashima K, et al.
Histochem Cell Biol
. 2015 Mar;
144(1):13-20.
PMID: 25812847
Cell differentiation is controlled by specific transcription factors. The functions and expression levels of these transcription factors are regulated by epigenetic modifications, such as histone modifications and cytosine methylation of...
17.
Kamiunten T, Ideno H, Shimada A, Nakamura Y, Kimura H, Nakashima K, et al.
Histochem Cell Biol
. 2014 Oct;
143(3):259-66.
PMID: 25294562
Tissue-specific gene expression is subjected to epigenetic and genetic regulation. Posttranslational modifications of histone tails alter the accessibility of nuclear proteins to DNA, thus affecting the activity of the regulatory...
18.
Shimada A, Wada S, Inoue K, Ideno H, Kamiunten T, Komatsu K, et al.
Histochem Cell Biol
. 2014 Feb;
142(2):205-15.
PMID: 24509807
Development of regenerative therapies for damaged tendons remains a great challenge, largely because of lack of information regarding the mechanisms responsible for differentiation of tenocytes. Mouse tenocytes have not been...
19.
Komatsu K, Shimada A, Shibata T, Wada S, Ideno H, Nakashima K, et al.
J Endocrinol
. 2013 Oct;
219(2):145-58.
PMID: 24096963
Bisphosphonates (BPs) are a major class of antiresorptive drug, and their molecular mechanisms of antiresorptive action have been extensively studied. Recent studies have suggested that BPs target bone-forming cells as...
20.
Ideno H, Shimada A, Imaizumi K, Kimura H, Abe M, Nakashima K, et al.
Gene Expr Patterns
. 2013 Jan;
13(3-4):84-90.
PMID: 23333759
Histone lysine methylation (HKM) is an epigenetic change that establishes cell-specific gene expression and determines cell fates. In this study, we investigated the expression patterns of histone H3 lysine 9...