Akiko Tsunemi
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Explore the profile of Akiko Tsunemi including associated specialties, affiliations and a list of published articles.
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25
Citations
214
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Recent Articles
1.
Nakamura Y, Kobayashi H, Fukuda N, Tanaka S, Murata Y, Hatanaka Y, et al.
Mol Biol Rep
. 2024 Jul;
51(1):790.
PMID: 38990390
Introduction: Creating induced pluripotent stem cells (iPSCs) from somatic cells of patients with genetic diseases offers a pathway to generate disease-specific iPSCs carrying genetic markers. Differentiating these iPSCs into renal...
2.
Kobayashi H, Satake E, Murata Y, Otsuka H, Tsunemi A, Azuma M, et al.
J Nephrol
. 2023 Jul;
36(8):2245-2256.
PMID: 37436574
Introduction: Recently, circulating neuroblastoma suppressor of tumorigenicity 1 (NBL1) was shown to be strongly associated with kidney disease progression and histological lesions in patients with diabetic kidney disease. This study...
3.
Kanezawa S, Moriyama M, Kanda T, Fukushima A, Masuzaki R, Sasaki-Tanaka R, et al.
Int J Mol Sci
. 2023 Mar;
24(5).
PMID: 36902037
Metabolic-dysfunction-associated fatty-liver disease (MAFLD) is the principal worldwide cause of liver disease. Individuals with nonalcoholic steatohepatitis (NASH) have a higher prevalence of small-intestinal bacterial overgrowth (SIBO). We examined gut-microbiota isolated...
4.
Baba S, Fukuda N, Kobayashi H, Tsunemi A, Akiya Y, Matsumoto T, et al.
J Pharmacol Sci
. 2023 Feb;
151(3):148-155.
PMID: 36828617
The cyclic adenosine monophosphate (cAMP)-response element binding protein (CREB)-glycogen synthase kinase 3β (GSK3β) signaling pathway was reported to be involved in the progression of autosomal dominant polycystic kidney diseases (ADPKD)....
5.
Otsuki T, Fukuda N, Chen L, Tsunemi A, Abe M
PLoS One
. 2022 Aug;
17(8):e0272917.
PMID: 36018840
We have demonstrated that complement 3 (C3) is upregulated and induces epithelial-mesenchymal transition (EMT) phenomenon and renal fibrosis in unilateral ureteral obstruction (UUO) kidney. We investigated roles of twist-related protein...
6.
Okamura M, Fukuda N, Horikoshi S, Kobayashi H, Tsunemi A, Akiya Y, et al.
Int J Mol Sci
. 2021 May;
22(9).
PMID: 33947045
Upstream stimulatory factor 1 (USF1) is a transcription factor that is increased in high-glucose conditions and activates the transforming growth factor (TGF)-β1 promoter. We examined the effects of synthetic pyrrole-imidazole...
7.
Horikoshi S, Fukuda N, Tsunemi A, Okamura M, Otsuki M, Endo M, et al.
Molecules
. 2020 Feb;
25(4).
PMID: 32093382
TGF-β1 has been known to induce diabetic nephropathy with renal fibrosis and glomerulosclerosis. DNA-recognized peptide compound pyrrole-imidazole (PI) polyamides as novel biomedicines can strongly bind promoter lesions of target genes...
8.
Tanaka S, Ueno T, Tsunemi A, Nagura C, Tahira K, Fukuda N, et al.
Hypertens Res
. 2018 Nov;
42(2):165-173.
PMID: 30464218
The circadian clock influences a multitude of cellular and biological processes, including blood pressure control. Spontaneously hypertensive rats (SHR) exhibit aberrant circadian rhythms affecting cardiovascular parameters, and they also have...
9.
Tanaka S, Ueno T, Tsunemi A, Nakamura Y, Kobayashi H, Hatanaka Y, et al.
Intern Med
. 2018 Sep;
58(2):251-257.
PMID: 30210108
A 40-year-old Japanese man presented with child-onset hypertriglyceridemia recently complicated by diabetes mellitus. The patient's diabetes mellitus was maintained, but he had persistent insulin resistance. The patient also had persistent...
10.
Higuchi T, Moriyama M, Fukushima A, Matsumura H, Matsuoka S, Kanda T, et al.
Oncotarget
. 2018 Jun;
9(40):26183-26194.
PMID: 29899851
Background: Excess iron is associated with non-alcoholic steatohepatitis (NASH). Results: mRNA expression of duodenal cytochrome b, divalent metal transporter 1, ferroportin 1, hepcidin, hephaestin and transferrin receptor 1 in liver...