Akiko Satoh
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Explore the profile of Akiko Satoh including associated specialties, affiliations and a list of published articles.
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33
Citations
1656
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Recent Articles
11.
Snyder-Warwick A, Satoh A, Santosa K, Imai S, Jablonka-Shariff A
Aging Cell
. 2018 Jun;
17(4):e12776.
PMID: 29851253
Neuromuscular decline occurs with aging. The neuromuscular junction (NMJ), the interface between motor nerve and muscle, also undergoes age-related changes. Aging effects on the NMJ components-motor nerve terminal, acetylcholine receptors...
12.
Satoh A, Iijima K
Brain Res
. 2017 Dec;
1702:17-28.
PMID: 29274876
The locus coeruleus (LC) is the noradrenaline (norepinephrine, NE)-containing nucleus in the brainstem and innervates into widespread brain regions. This LC-NE system plays a critical role in a variety of...
13.
Satoh A, Imai S, Guarente L
Nat Rev Neurosci
. 2017 May;
18(6):362-374.
PMID: 28515492
In mammals, recent studies have demonstrated that the brain, the hypothalamus in particular, is a key bidirectional integrator of humoral and neural information from peripheral tissues, thus influencing ageing both...
14.
Satoh A, Brace C, Rensing N, Imai S
Aging Cell
. 2014 Dec;
14(2):209-18.
PMID: 25546159
The dorsomedial hypothalamus (DMH) controls a number of essential physiological responses. We have demonstrated that the DMH plays an important role in the regulation of mammalian aging and longevity. To...
15.
Satoh A, Imai S
Nat Commun
. 2014 Jun;
5:4211.
PMID: 24967620
Sirtuins regulate numerous important biological processes in mammals, including various age-associated pathophysiologies. However, whether sirtuins are critical to control ageing and longevity in mammals has been controversial. Recent studies have...
16.
17.
Yokozawa T, Satoh A, Kim Y
Biosci Biotechnol Biochem
. 2013 Oct;
77(10):2056-60.
PMID: 24096652
Proanthocyanidin (a persimmon-peel extract) is known to have potent antioxidative effects, but its protective action specifically against cellular damage has not been fully explored. In this work, we investigated the...
18.
Satoh A, Brace C, Rensing N, Cliften P, Wozniak D, Herzog E, et al.
Cell Metab
. 2013 Sep;
18(3):416-30.
PMID: 24011076
The mammalian Sir2 ortholog Sirt1 plays an important role in metabolic regulation. However, the role of Sirt1 in the regulation of aging and longevity is still controversial. Here we demonstrate...
19.
Satoh A, Stein L, Imai S
Handb Exp Pharmacol
. 2011 Sep;
206:125-62.
PMID: 21879449
Ever since the discovery of sirtuins a decade ago, interest in this family of NAD-dependent deacetylases has exploded, generating multiple lines of evidence implicating sirtuins as evolutionarily conserved regulators of...
20.
Ishihara H, Tanaka I, Yakumaru H, Tanaka M, Satoh A, Ishiwata A, et al.
Radiat Res
. 2011 Mar;
175(3):367-74.
PMID: 21388280
Damage to intestine is a serious problem after accidental radiation exposure. To examine substances to ameliorate damage by postirradiation administration, we focused on the regeneration process after irradiation of the...