Akihiro Ichikawa
Overview
Explore the profile of Akihiro Ichikawa including associated specialties, affiliations and a list of published articles.
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Articles
21
Citations
581
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0
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Recent Articles
1.
Ito A, Hashimoto M, Tanihata J, Matsubayashi S, Sasaki R, Fujimoto S, et al.
J Cachexia Sarcopenia Muscle
. 2022 Apr;
13(3):1864-1882.
PMID: 35373498
Background: Sarcopenia is characterized by the loss of skeletal muscle mass and strength and is associated with poor prognosis in patients with chronic obstructive pulmonary disease (COPD). Cigarette smoke (CS)...
2.
Araya J, Saito N, Hosaka Y, Ichikawa A, Kadota T, Fujita Y, et al.
J Immunol
. 2021 Jun;
207(1):65-76.
PMID: 34135057
Insufficient autophagic degradation has been implicated in accelerated cellular senescence during chronic obstructive pulmonary disease (COPD) pathogenesis. Aging-linked and cigarette smoke (CS)-induced functional deterioration of lysosomes may be associated with...
3.
Endoh H, Ichikawa A, Yamamoto R, Shiozawa S, Nishizawa N, Satoh Y, et al.
Int J Clin Oncol
. 2020 Sep;
26(1):87-94.
PMID: 32951076
Background: 2-[F] Fluoro-D-deoxyglucose positron emission tomography (FDG-PET) is an appropriate diagnostic procedure for staging lung cancer. However, accurate evaluation of lymph node (LN) metastases by PET is controversial owing to...
4.
Ichikawa A, Fujita Y, Hosaka Y, Kadota T, Ito A, Yagishita S, et al.
Cancer Sci
. 2020 Aug;
111(11):4154-4165.
PMID: 32860290
Chaperone-mediated autophagy (CMA) is a lysosomal degradation pathway of selective soluble proteins. Lysosome-associated membrane protein type 2a (LAMP2A) is the key receptor protein of CMA; downregulation of LAMP2A leads to...
5.
Hosaka Y, Araya J, Fujita Y, Kadota T, Tsubouchi K, Yoshida M, et al.
J Immunol
. 2020 Jul;
205(5):1256-1267.
PMID: 32699159
Cigarette smoke (CS) induces accumulation of misfolded proteins with concomitantly enhanced unfolded protein response (UPR). Increased apoptosis linked to UPR has been demonstrated in chronic obstructive pulmonary disease (COPD) pathogenesis....
6.
Endoh H, Yamamoto R, Ichikawa A, Shiozawa S, Nishizawa N, Satoh Y, et al.
Clin Lung Cancer
. 2020 Jul;
22(3):218-224.
PMID: 32654926
Introduction: 2-[F] Fluoro-d-deoxyglucose (FDG) positron emission tomography (PET) is a relevant diagnostic procedure for staging lung cancer. However, accurate evaluation of lymph node metastases by PET is controversial because of...
7.
Tsubouchi K, Araya J, Yoshida M, Sakamoto T, Koumura T, Minagawa S, et al.
J Immunol
. 2019 Sep;
203(8):2076-2087.
PMID: 31534007
The imbalanced redox status in lung has been widely implicated in idiopathic pulmonary fibrosis (IPF) pathogenesis. To regulate redox status, hydrogen peroxide must be adequately reduced to water by glutathione...
8.
Yoshida M, Minagawa S, Araya J, Sakamoto T, Hara H, Tsubouchi K, et al.
Nat Commun
. 2019 Jul;
10(1):3145.
PMID: 31316058
Ferroptosis is a necrotic form of regulated cell death (RCD) mediated by phospholipid peroxidation in association with free iron-mediated Fenton reactions. Disrupted iron homeostasis resulting in excessive oxidative stress has...
9.
Kawamoto H, Hara H, Araya J, Ichikawa A, Fujita Y, Utsumi H, et al.
Cancers (Basel)
. 2019 Jun;
11(6).
PMID: 31163629
: Prostaglandin E2 (PGE2) is metabolized to prostaglandin E-major urinary metabolite (PGE-MUM). Enhanced cyclooxygenase-2 (COX-2) expression demonstrated in lung adenocarcinoma indicates increased PGE-MUM levels in patients with lung adenocarcinoma. :...
10.
Saito N, Araya J, Ito S, Tsubouchi K, Minagawa S, Hara H, et al.
J Immunol
. 2019 Jan;
202(5):1428-1440.
PMID: 30692212
Downregulation of lamin B1 has been recognized as a crucial step for development of full senescence. Accelerated cellular senescence linked to mechanistic target of rapamycin kinase (MTOR) signaling and accumulation...