Akemi Takata
Overview
Explore the profile of Akemi Takata including associated specialties, affiliations and a list of published articles.
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Articles
24
Citations
667
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0
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Recent Articles
1.
Takata A, Otsuka M, Kishikawa T, Yamagami M, Ishibashi R, Sekiba K, et al.
Oncotarget
. 2017 Oct;
8(39):64840-64852.
PMID: 29029395
Liver fibrosis, leading to cirrhosis and liver failure, can occur after chronic liver injury. The transition of hepatic stellate cells (HSCs) from quiescent cells into proliferative and fibrogenic cells is...
2.
Yoshikawa T, Wu J, Otsuka M, Kishikawa T, Suzuki N, Takata A, et al.
Gastroenterology
. 2016 Nov;
152(3):631-643.
PMID: 27825961
Background & Aims: Little is known about the mechanisms by which chronic inflammation contributes to carcinogenesis, such as the development of colon tumors in patients with inflammatory bowel diseases. Specific...
3.
Otsuka M, Kishikawa T, Yoshikawa T, Yamagami M, Ohno M, Takata A, et al.
J Hum Genet
. 2016 May;
62(1):75-80.
PMID: 27225852
The biological roles of microRNAs (miRNAs) have been extensively studied. miRNA122 represents more than half of the miRNAs expressed in the liver and has various physiological and pathological functions, which...
4.
Takata A, Otsuka M, Ohno M, Kishikawa T, Yoshikawa T, Koike K
Sci Rep
. 2016 Mar;
6:23237.
PMID: 26979389
The interplay between viral and host factors plays a major role in viral pathogenesis. Hepatitis B virus (HBV) infection is a global health problem that leads to liver cirrhosis and...
5.
Kishikawa T, Otsuka M, Ohno M, Yoshikawa T, Takata A, Koike K
World J Gastroenterol
. 2015 Aug;
21(28):8527-40.
PMID: 26229396
Pancreatic cancer remains difficult to treat and has a high mortality rate. It is difficult to diagnose early, mainly due to the lack of screening imaging modalities and specific biomarkers....
6.
Yoshikawa T, Wu J, Otsuka M, Kishikawa T, Ohno M, Shibata C, et al.
Nucleic Acids Res
. 2015 Jul;
43(15):7577-89.
PMID: 26187994
The reduced expression levels and functional impairment of global miRNAs are related to various human diseases, including cancers. However, relatively little is known about how global miRNA function may be...
7.
Ohno M, Otsuka M, Kishikawa T, Yoshikawa T, Takata A, Koike K
World J Gastroenterol
. 2015 Jun;
21(23):7084-8.
PMID: 26109795
Hepatitis B virus (HBV) infection is a major global health problem. Although current therapies, such as the use of nucleos(t)ide analogs, inhibit HBV replication efficiently, they do not eliminate covalently...
8.
Shibata C, Otsuka M, Kishikawa T, Yoshikawa T, Ohno M, Takata A, et al.
Mol Cell Ther
. 2015 Jun;
1:5.
PMID: 26056570
Expanding knowledge about the crucial roles of microRNAs (miRNAs) in human diseases has led to the idea that miRNAs may be novel, promising therapeutic targets against various pathological conditions. The...
9.
Kishikawa T, Otsuka M, Tan P, Ohno M, Sun X, Yoshikawa T, et al.
Oncotarget
. 2015 Apr;
6(10):8339-52.
PMID: 25826076
Reduced expression of microRNA122 (miR122), a liver-specific microRNA, is frequent in hepatocellular carcinoma (HCC). However, its biological significances remain poorly understood. Because deregulated amino acid levels in cancers can affect...
10.
Shibata C, Otsuka M, Kishikawa T, Ohno M, Yoshikawa T, Takata A, et al.
World J Hepatol
. 2015 Jan;
7(1):1-6.
PMID: 25624991
MicroRNAs (miRNAs) are small, noncoding RNA molecules that regulate gene expression posttranscriptionally, targeting thousands of messenger RNAs. Long noncoding RNAs (lncRNAs), another class of noncoding RNAs, have been determined to...