Ajith Harish
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Explore the profile of Ajith Harish including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
191
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Recent Articles
1.
Harish A
QRB Discov
. 2024 Apr;
5:e3.
PMID: 38616890
The formulation and testing of hypotheses using 'big biology data' often lie at the interface of computational biology and structural biology. The Protein Data Bank (PDB), which was established about...
2.
Harish A, Lopes Pinto F, Eriksson S, Johansson A
BMC Genomics
. 2024 Jan;
25(1):89.
PMID: 38254050
Several indigenous cattle breeds in Sweden are endangered. Conservation of their genetic diversity and genomic characterization is a priority.Whole-genome sequences (WGS) with a mean coverage of 25X, ranging from 14...
3.
Maghembe R, Michael A, Harish A, Nyandoro S, Lyantagaye S, Hati-Kaul R
Microbiol Resour Announc
. 2021 Apr;
10(16).
PMID: 33888498
The genus includes cyanobacterial species used for industrial production of dietary supplements and nutraceutical agents. The metagenome-assembled genome of sp. strain BM01 from Big Momela Lake, Tanzania, was 6,228,312 bp...
4.
Harish A, Morrison D
F1000Res
. 2020 Jul;
9:112.
PMID: 32685134
Locating the root node of the "tree of life" (ToL) is one of the hardest problems in phylogenetics, given the time depth. The root-node, or the universal common ancestor (UCA),...
5.
Harish A
PeerJ
. 2018 Oct;
6:e5770.
PMID: 30357005
The recognition of the group Archaea as a major branch of the tree of life (ToL) prompted a new view of the evolution of biodiversity. The genomic representation of archaeal...
6.
Reply to Caetano-Anollés et al. comment on "Empirical genome evolution models root the tree of life"
Harish A, Kurland C
Biochimie
. 2018 Apr;
149:137-138.
PMID: 29631014
We recently analyzed the robustness of competing evolution models developed to identify the root of the Tree of Life: 1) An empirical Sankoff parsimony (ESP) model (Harish and Kurland, 2017),...
7.
Harish A, Kurland C
J Theor Biol
. 2017 Jul;
434:88-98.
PMID: 28754286
Lynn Sagan's conjecture (1967) that three of the fundamental organelles observed in eukaryote cells, specifically mitochondria, plastids and flagella were once free-living primitive (prokaryotic) cells was accepted after considerable opposition....
8.
Harish A, Kurland C
Biochimie
. 2017 May;
138:137-155.
PMID: 28478110
A reliable phylogenetic reconstruction of the evolutionary history of contemporary species depends on a robust identification of the universal common ancestor (UCA) at the root of the Tree of Life...
9.
Harish A, Kurland C
Biochimie
. 2017 May;
138:168-183.
PMID: 28461155
We reconstructed a global tree of life (ToL) with non-reversible and non-stationary models of genome evolution that root trees intrinsically. We implemented Bayesian model selection tests and compared the statistical...
10.
Harish A, Abroi A, Gough J, Kurland C
Genome Biol Evol
. 2016 Aug;
8(8):2474-81.
PMID: 27497315
The evolutionary origins of viruses according to marker gene phylogenies, as well as their relationships to the ancestors of host cells remains unclear. In a recent article Nasir and Caetano-Anollés...