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Ajit P Yoganathan

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Articles 302
Citations 5278
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Recent Articles
1.
Alexander P, Di Nardo M, Combes A, Vogel A, Antonini M, Barrett N, et al.
Lancet Child Adolesc Health . 2024 Sep; 8(10):773-780. PMID: 39299748
Extracorporeal membrane oxygenation (ECMO) is a high-risk and low-volume life support with increasing clinical study. However, heterogenous outcome definitions impede data assimilation into evidence to guide practice. The Academic Research...
2.
Sadri V, Midha P, Madukauwa-David I, Kamioka N, Trusty P, Nair P, et al.
Cardiovasc Eng Technol . 2024 Sep; 15(6):749-759. PMID: 39285066
Purpose: Neo-sinus flow stasis has ben correlated with transcatheter heart valve (THV) thrombosis severity and occurrence. Standard benchtop flow field quantification techniques require optical access or modified prosthesis models that...
3.
Natarajan T, Singh-Gryzbon S, Chen H, Sadri V, Ruile P, Neumann F, et al.
Cardiovasc Eng Technol . 2024 Apr; 15(4):463-480. PMID: 38653932
Purpose: Patient-specific simulations of transcatheter aortic valve (TAV) using computational fluid dynamics (CFD) often rely on assumptions regarding proximal and distal anatomy due to the limited availability of high-resolution imaging...
4.
Kim J, Sadri V, Chen H, Bhat S, Kohli K, Makkar R, et al.
Ann Biomed Eng . 2023 Nov; 52(2):425-439. PMID: 37922056
Patient-specific aortic geometry and its influence on the flow in the vicinity of Transcatheter Aortic Valve (TAV) has been highlighted in numerous studies using both in silico and in vitro...
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Sadri V, Kohli K, Ncho B, Inci E, Perdoncin E, Lisko J, et al.
J Thorac Cardiovasc Surg . 2023 Apr; 166(4):e130-e141. PMID: 37086238
Background: Leaflet thrombosis after surgical aortic valve replacement (SAVR) and transcatheter aortic valve replacement (TAVR) may be caused by blood flow stagnation in the native and neosinus regions. To date,...
6.
Ratnayaka K, Wei Z, Ryan J, Heyden C, Narayan H, Slesnick T, et al.
JACC Case Rep . 2023 Mar; 10:101760. PMID: 36974056
The authors report a closed-chest, transcatheter large-vessel connection (hepatic conduit to azygous vein) to reverse pulmonary arteriovenous malformations in a 10-year-old patient after Fontan for heterotaxy/interrupted inferior vena cava, with...
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Salim M, Villa-Roel N, Vogel B, Jo H, Yoganathan A
Front Cardiovasc Med . 2022 Nov; 9:1002067. PMID: 36419483
HIF1A is significantly upregulated in calcified human aortic valves (AVs). Furthermore, HIF1A inhibitor PX-478 was shown to inhibit AV calcification under static and disturbed flow conditions. Since elevated stretch is...
9.
Ncho B, Kohli K, Sadri V, Yoganathan A
Cardiovasc Eng Technol . 2022 Nov; 14(2):182-193. PMID: 36357649
Purpose: Leaflet thrombosis is a potentially fatal complication after transcatheter aortic valve replacement (TAVR). Blood flow stagnation in the neo-sinus and aortic sinuses are associated with increased thrombus severity. Native...
10.
Brener M, Hamandi M, Hong E, Pizano A, Harloff M, Garner E, et al.
J Thorac Cardiovasc Surg . 2022 Sep; 167(4):1263-1275.e3. PMID: 36153166
Objective: Implantation of a transcatheter valve-in-mitral annular calcification (ViMAC) has emerged as an alternative to traditional surgical mitral valve (MV) replacement. Previous studies evaluating ViMAC aggregated transseptal, transapical, and transatrial...