Ajay Vir Singh
Overview
Explore the profile of Ajay Vir Singh including associated specialties, affiliations and a list of published articles.
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30
Citations
112
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Recent Articles
1.
Saha S, Roy S, Hazra A, Das D, Kumar V, Singh A, et al.
Proc Natl Acad Sci U S A
. 2025 Mar;
122(10):e2404106122.
PMID: 40035756
The tuberculosis-causing agent (M.tb) establishes its niche inside macrophages by secretion of several virulence factors and engaging many host factors. Mycobacterial infection of macrophages results in a proinflammatory trigger-mediated secretion...
2.
Kushwaha S, Goel A, Singh A
Infect Disord Drug Targets
. 2024 Nov;
PMID: 39506419
Non-coding RNAs (ncRNAs), specifically MicroRNAs or miRNAs, are now under-stood to be essential regulators in the complex field of gene expression. By selectively bind-ing to certain mRNA targets, these tiny...
3.
Kumar R, Sohal J, Singh A, Chauhan D
Mol Biol Rep
. 2024 Oct;
51(1):1091.
PMID: 39446249
Background: Mono-resistance to rifampicin/isoniazid increases poor treatment outcomes and the risk of multi-drug resistance (MDR) in tuberculosis (TB) patients. Limited information exists about mono-resistance status of TB patients in Uttar...
4.
Kushwaha S, Yadav R, Kumar R, Kumar S, Chauhan D, Singh A
Indian J Med Res
. 2024 Oct;
159(6):653-662.
PMID: 39382473
Background & objectives Despite the evidence of population differences in miRNA expression, limited information is available about the expression profile of miRNAs in Indian tuberculosis (TB) patients. The present study...
5.
Yadav R, Singh A, Kushwaha S, Chauhan D
Indian J Med Res
. 2024 Apr;
159(2):163-180.
PMID: 38577857
From an initial thought of being used as a cellular garbage bin to a promising target for liquid biopsies, the role of exosomes has drastically evolved in just a few...
6.
Davuluri K, Singh A, Yadav V, Singh A, Singh S, Chauhan D
BMC Immunol
. 2023 Nov;
24(1):49.
PMID: 38036985
Background: Tumor necrosis factor (TNF) is known to promote T cell migration and increase the expression of vascular endothelial growth factor (VEGF) and chemokines. The administration of Xpro-1595, a dominant-negative...
7.
Davuluri K, Singh A, Singh A, Chaudhary P, Raman S, Kushwaha S, et al.
Microbiol Spectr
. 2023 Jan;
:e0319722.
PMID: 36719189
The majority of preclinical research has shown that Mycobacterium tuberculosis can modify host lipids in various ways. To boost its intramacrophage survival, M. tuberculosis causes host lipids to build up,...
8.
Singh A, Yadav V, Chauhan D, Singh S
Indian J Med Res
. 2022 Dec;
156(1):21-30.
PMID: 36510895
Tuberculosis (TB) caused by Mycobacterium tuberculosis is a leading cause of human deaths due to any infectious disease worldwide. However, infection of Mycobacterium bovis, primarily an animal pathogen, also leads...
9.
Davuluri K, Singh A, Kumar V, Singh S, Singh A, Kumar S, et al.
Tuberculosis (Edinb)
. 2022 Jun;
135:102224.
PMID: 35763913
Pathogenic mycobacteria induce and accelerate blood vessel formation driven by extensive inflammation during granuloma formation, which is a central feature of mycobacterial pathogenesis. Tumor necrosis factor-alpha (TNF-α) enhances the expression...
10.
Saha S, Hazra A, Ghatak D, Singh A, Roy S, BoseDasgupta S
Front Immunol
. 2021 Oct;
12:687044.
PMID: 34630380
Phagosome-lysosome fusion in innate immune cells like macrophages and neutrophils marshal an essential role in eliminating intracellular microorganisms. In microbe-challenged macrophages, phagosome-lysosome fusion occurs 4 to 6 h after the...