Aizhuo Liu
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Explore the profile of Aizhuo Liu including associated specialties, affiliations and a list of published articles.
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11
Citations
83
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Recent Articles
1.
Xia Y, Yuwen T, Liu A, Kalodimos C
J Biomol NMR
. 2021 Mar;
75(2-3):133-142.
PMID: 33745068
A unique aspect of NMR is its capacity to provide integrated insight into both the structure and intrinsic dynamics of biomolecules. Chemical exchange phenomena that often serve as probes of...
2.
The activation loop of PIP5K functions as a membrane sensor essential for lipid substrate processing
Liu A, Sui D, Wu D, Hu J
Sci Adv
. 2017 Feb;
2(11):e1600925.
PMID: 28138522
Phosphatidylinositol 4-phosphate 5-kinase (PIP5K), a representative member of the phosphatidylinositol phosphate kinase (PIPK) family, is a major enzyme that biosynthesizes the signaling molecule PI(4,5)P (phosphatidylinositol 4,5-bisphosphate) in eukaryotic cells. The...
3.
Achila D, Liu A, Banerjee R, Li Y, Martinez-Hackert E, Zhang J, et al.
Biochem J
. 2014 Oct;
465(2):325-35.
PMID: 25330773
Many human pathogens have strict host specificity, which affects not only their epidemiology but also the development of animal models and vaccines. Complement Factor H (FH) is recruited to pneumococcal...
4.
Chen B, Himes P, Liu Y, Zhang Y, Lu Z, Liu A, et al.
J Bacteriol
. 2014 Mar;
196(12):2131-42.
PMID: 24584501
SpoIIID is evolutionarily conserved in endospore-forming bacteria, and it activates or represses many genes during sporulation of Bacillus subtilis. An SpoIIID monomer binds DNA with high affinity and moderate sequence...
5.
Wang J, Sklenak S, Liu A, Felczak K, Wu Y, Li Y, et al.
Biochemistry
. 2012 Jan;
51(1):475-86.
PMID: 22208667
Yeast cytosine deaminase (yCD) catalyzes the hydrolytic deamination of cytosine to uracil as well as the deamination of the prodrug 5-fluorocytosine (5FC) to the anticancer drug 5-fluorouracil. In this study,...
6.
Liu A, Wang J, Lu Z, Yao L, Li Y, Yan H
Chembiochem
. 2008 Nov;
9(17):2860-71.
PMID: 18973166
The configuration and hydrogen-bonding network of side-chain amides in a 35 kDa protein were determined by measuring differential and trans-hydrogen-bond H/D isotope effects by using the isotopomer-selective (IS)-TROSY technique, which...
7.
Kron M, Cichanowicz S, Hendrick A, Liu A, Leykam J, Kuhn L
Protein Sci
. 2008 Apr;
17(6):983-9.
PMID: 18411421
Diagnosis of eukaryotic parasitic infection using antibody-based tests such as ELISAs (enzyme-linked immunosorbent assays) is often problematic because of the need to differentiate between homologous host and pathogen proteins and...
8.
Liu A, Lu Z, Wang J, Yao L, Li Y, Yan H
J Am Chem Soc
. 2008 Feb;
130(8):2428-9.
PMID: 18247612
No abstract available.
9.
Liu A, Yao L, Li Y, Yan H
J Magn Reson
. 2007 Mar;
186(2):319-26.
PMID: 17347000
By using the mixed solvent of 50% H2O/50% D2O and employing deuterium decoupling, TROSY experiments exclusively detect NMR signals from semideuterated isotopomers of carboxamide groups with high sensitivities for proteins...
10.
Liu A, Li Y, Yao L, Yan H
J Biomol NMR
. 2006 Nov;
36(4):205-14.
PMID: 17091334
A new strategy for the simultaneous NMR assignment of both backbone and side chain amides in large proteins with isotopomer-selective transverse-relaxation-optimized spectroscopy (IS-TROSY) is reported. The method considers aspects of...