Aishlin Hassan
Overview
Explore the profile of Aishlin Hassan including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
220
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Recent Articles
1.
Culver-Cochran A, Hassan A, Hueneman K, Choi K, Ma A, VanCauwenbergh B, et al.
Nat Commun
. 2024 Oct;
15(1):9189.
PMID: 39448591
Acute myeloid leukemia (AML) is a deadly hematopoietic malignancy. Although many patients achieve complete remission with standard induction therapy, a combination of cytarabine and anthracycline, ~40% of patients have induction...
2.
Kumar S, Vassallo J, Nattamai K, Hassan A, Vollmer A, Karns R, et al.
Aging Cell
. 2024 Sep;
23(10):e14324.
PMID: 39236298
Aged hematopoietic stem cells (HSCs) show reduced reconstitution potential, limiting their use in transplantation settings in the clinic. We demonstrate here that exposure of aged HSCs ex vivo to a...
3.
Kumar S, Vassallo J, Nattamai K, Hassan A, Karns R, Vollmer A, et al.
EMBO Rep
. 2023 Mar;
24(5):e55373.
PMID: 36943011
Upon ex vivo culture, hematopoietic stem cells (HSCs) quickly lose potential and differentiate into progenitors. The identification of culture conditions that maintain the potential of HSCs ex vivo is therefore...
4.
Sakabe M, Thompson M, Chen N, Verba M, Hassan A, Lu R, et al.
Elife
. 2022 Dec;
11.
PMID: 36479975
The regeneration potential of the mammalian heart is incredibly limited, as cardiomyocyte proliferation ceases shortly after birth. β-adrenergic receptor (β-AR) blockade has been shown to improve heart functions in response...
5.
Nalapareddy K, Hassan A, Sampson L, Zheng Y, Geiger H
iScience
. 2021 Apr;
24(4):102362.
PMID: 33870147
Homeostasis in the intestinal epithelium is maintained by Lgr5-positive intestinal stem cells (ISCs) located at the base of the crypt. The function of ISCs is reduced upon aging which leads...
6.
Kumar S, Nattamai K, Hassan A, Amoah A, Karns R, Zhang C, et al.
Leukemia
. 2020 Oct;
35(6):1751-1762.
PMID: 33077869
Shwachman-Diamond syndrome (SDS) is a bone marrow failure (BMF) syndrome associated with an increased risk of myelodysplasia and leukemia. The molecular mechanisms of SDS are not fully understood. We report...
7.
Sakabe M, Fan J, Odaka Y, Liu N, Hassan A, Duan X, et al.
Proc Natl Acad Sci U S A
. 2017 Oct;
114(41):10918-10923.
PMID: 28973878
Angiogenesis and vascular remodeling are essential for the establishment of vascular networks during organogenesis. Here we show that the Hippo signaling pathway effectors YAP and TAZ are required, in a...
8.
Zhang L, He X, Liu L, Jiang M, Zhao C, Wang H, et al.
Dev Cell
. 2016 Jun;
37(6):582.
PMID: 27326936
No abstract available.
9.
Hu J, Al-Waili D, Hassan A, Fan G, Xin M, Hao J
Neuroscience
. 2016 May;
329:30-42.
PMID: 27132231
The present study generated a novel DNA complex to specifically target endothelial NF-κB to inhibit cerebral vascular inflammation. This DNA complex (GS24-NFκB) contains a DNA decoy which inhibits NF-κB activity,...
10.
Zhang L, He X, Liu L, Jiang M, Zhao C, Wang H, et al.
Dev Cell
. 2016 Feb;
36(3):316-30.
PMID: 26859354
Establishment and maintenance of CNS glial cell identity ensures proper brain development and function, yet the epigenetic mechanisms underlying glial fate control remain poorly understood. Here, we show that the...