Aine Fanning
Overview
Explore the profile of Aine Fanning including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
478
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0
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Recent Articles
1.
OMahony C, Clooney A, Clarke S, Aguilera M, Gavin A, Simnica D, et al.
Int J Mol Sci
. 2023 Feb;
24(3).
PMID: 36768196
Environmental factors, including westernised diets and alterations to the gut microbiota, are considered risk factors for inflammatory bowel diseases (IBD). The mechanisms underpinning diet-microbiota-host interactions are poorly understood in IBD....
2.
Flood P, Fanning A, Woznicki J, Crowley T, Christopher A, Vaccaro A, et al.
Am J Physiol Gastrointest Liver Physiol
. 2022 Sep;
323(5):G439-G460.
PMID: 36165492
DNA sensor pathways can initiate inflammasome, cell death, and type I interferon (IFN) signaling in immune-mediated inflammatory diseases (IMIDs), including type I interferonopathies. We investigated the involvement of these pathways...
3.
Saiz-Gonzalo G, Hanrahan N, Rossini V, Singh R, Ahern M, Kelleher M, et al.
Front Immunol
. 2021 Aug;
12:655960.
PMID: 34394073
Carcinoembryogenic antigen cellular adhesion molecules (CEACAMs) are intercellular adhesion molecules highly expressed in intestinal epithelial cells. CEACAM1, -3, -5, -6, -7 are altered in patients suffering from colon cancer and...
4.
Aguilera M, Rossini V, Hickey A, Simnica D, Grady F, Felice V, et al.
Int J Mol Sci
. 2021 Aug;
22(15).
PMID: 34361102
Interactions between the intestinal microbiota, immune system and nervous system are essential for homeostasis in the gut. Inflammasomes contribute to innate immunity and brain-gut interactions, but their role in microbiota-neuro-immune...
5.
Nychyk O, Barton W, Rudolf A, Boscaini S, Walsh A, Bastiaanssen T, et al.
Cell Rep
. 2021 May;
35(6):109093.
PMID: 33979605
We investigated how protein quantity (10%-30%) and quality (casein and whey) interact with dietary fat (20%-55%) to affect metabolic health in adult mice. Although dietary fat was the main driver...
6.
Woznicki J, Flood P, Bustamante-Garrido M, Stamou P, Moloney G, Fanning A, et al.
Cell Death Dis
. 2020 Jan;
11(1):68.
PMID: 31988296
Proteins of the BCL-2 family are evolutionarily conserved modulators of apoptosis that function as sensors of cellular integrity. Over the past three decades multiple BCL-2 family members have been identified,...
7.
Cronin O, Barton W, Skuse P, Penney N, Garcia-Perez I, Murphy E, et al.
mSystems
. 2018 May;
3(3).
PMID: 29719871
Many components of modern living exert influence on the resident intestinal microbiota of humans with resultant impact on host health. For example, exercise-associated changes in the diversity, composition, and functional...
8.
Houston A, Williams J, Lenac Rovis T, Shanley D, ORiordan R, Kiely P, et al.
MAbs
. 2016 Mar;
8(3):491-500.
PMID: 26926266
Pregnancy-specific glycoproteins (PSGs) are immunoglobulin superfamily members related to the carcinoembryonic antigen-related cell adhesion molecule (CEACAM) family and are encoded by 10 genes in the human. They are secreted at...
9.
Brint E, MacSharry J, Fanning A, Shanahan F, Quigley E
Am J Gastroenterol
. 2010 Nov;
106(2):329-36.
PMID: 21102570
Objectives: The pathogenesis of irritable bowel syndrome (IBS) is poorly understood. One contributory factor may be low-grade mucosal inflammation, perhaps initiated by the microbiota. Toll-like receptors (TLRs) are a family...
10.
Sibartie S, OHara A, Ryan J, Fanning A, OMahony J, ONeill S, et al.
BMC Immunol
. 2009 Oct;
10:54.
PMID: 19814810
Background: Human intestinal epithelial cells (IECs) secrete the chemokine CCL20 in response to infection by various enteropathogenic bacteria or exposure to bacterial flagellin. CCL20 recruits immature dendritic cells and lymphocytes...