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» Authors » Aiman A Haqqani

Aiman A Haqqani

Explore the profile of Aiman A Haqqani including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 7
Citations 153
Followers 0
Related Specialties
Microbiology
Science
Chemistry
Top 10 Co-Authors
John C Tilton
Caroline O Tabler
Mark B Lucera
Samantha L Marek
Carisa A Tilton
Curtis Dobrowolski
Miles Davenport
David J McDonald
Mark Connors
Hongxia Mao
Published In
J Virol
Antiviral Res
Virol J
J Virol Methods
Anal Chem
Affiliations
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Recent Articles
1.
Nanoscale flow cytometry reveals interpatient variability in HIV protease activity that correlates with viral infectivity and identifies drug-resistant viruses
Bonar M, Tabler C, Haqqani A, Lapointe L, Galiatsos J, Joussef-Pina S, et al.
Sci Rep . 2020 Oct; 10(1):18101. PMID: 33093566
HIV encodes an aspartyl protease that is activated during, or shortly after, budding of viral particles from the surface of infected cells. Protease-mediated cleavage of viral polyproteins is essential to...
2.
A Targeted Mass Spectrometry Assay for Detection of HIV Gag Protein Following Induction of Latent Viral Reservoirs
Schlatzer D, Haqqani A, Li X, Dobrowolski C, Chance M, Tilton J
Anal Chem . 2017 May; 89(10):5325-5332. PMID: 28467046
During early infection, HIV-1 establishes a reservoir of latently infected cells that persist during antiretroviral therapy. These reservoirs are considered the primary obstacle to eradicating HIV-1 from patients, and multiple...
3.
Central memory CD4+ T cells are preferential targets of double infection by HIV-1
Haqqani A, Marek S, Kumar J, Davenport M, Wang H, Tilton J
Virol J . 2015 Nov; 12:184. PMID: 26559763
Background: Template switching between two distinct HIV-1 RNA genomes during reverse transcription gives rise to recombinant viruses that greatly expand the genetic diversity of HIV-1 and have adverse implications for...
4.
The histone deacetylase inhibitor vorinostat (SAHA) increases the susceptibility of uninfected CD4+ T cells to HIV by increasing the kinetics and efficiency of postentry viral events
Lucera M, Tilton C, Mao H, Dobrowolski C, Tabler C, Haqqani A, et al.
J Virol . 2014 Jul; 88(18):10803-12. PMID: 25008921
Unlabelled: Latently infected cells remain a primary barrier to eradication of HIV-1. Over the past decade, a better understanding of the molecular mechanisms by which latency is established and maintained...
5.
CD4+ memory stem cells are infected by HIV-1 in a manner regulated in part by SAMHD1 expression
Tabler C, Lucera M, Haqqani A, McDonald D, Migueles S, Connors M, et al.
J Virol . 2014 Feb; 88(9):4976-86. PMID: 24554663
Unlabelled: CD4(+) and CD8(+) memory T cells with stem cell-like properties (T(SCM) cells) have been identified in mice, humans, and nonhuman primates and are being investigated for antitumor and antiviral...
6.
A combination HIV reporter virus system for measuring post-entry event efficiency and viral outcome in primary CD4+ T cell subsets
Tilton C, Tabler C, Lucera M, Marek S, Haqqani A, Tilton J
J Virol Methods . 2013 Sep; 195:164-9. PMID: 24025341
Fusion between the viral membrane of human immunodeficiency virus (HIV) and the host cell marks the end of the HIV entry process and the beginning of a series of post-entry...
7.
Entry inhibitors and their use in the treatment of HIV-1 infection
Haqqani A, Tilton J
Antiviral Res . 2013 Apr; 98(2):158-70. PMID: 23541872
Entry of HIV into target cells is a complex, multi-stage process involving sequential attachment and CD4 binding, coreceptor binding, and membrane fusion. HIV entry inhibitors are a complex group of...