Aida Karachi
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Explore the profile of Aida Karachi including associated specialties, affiliations and a list of published articles.
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20
Citations
639
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Recent Articles
1.
Frain M, Thomas N, Yan S, Karachi A, Dastmalchi F, Ebrahim G, et al.
Neurosurg Focus
. 2024 Nov;
57(5):E10.
PMID: 39486063
Objective: The objective of this study was to develop a murine system for the delivery of laser interstitial thermotherapy (LITT) with probe-based thermometry as a model for human glioblastoma treatment...
2.
Mendez-Gomez H, DeVries A, Castillo P, von Roemeling C, Qdaisat S, Stover B, et al.
Cell
. 2024 May;
187(10):2521-2535.e21.
PMID: 38697107
Cancer immunotherapy remains limited by poor antigenicity and a regulatory tumor microenvironment (TME). Here, we create "onion-like" multi-lamellar RNA lipid particle aggregates (LPAs) to substantially enhance the payload packaging and...
3.
Mendez-Gomez H, DeVries A, Castillo P, Stover B, Qdaisat S, von Roemeling C, et al.
medRxiv
. 2023 Mar;
PMID: 36993772
Messenger RNA (mRNA) has emerged as a remarkable tool for COVID-19 prevention but its use for induction of therapeutic cancer immunotherapy remains limited by poor antigenicity and a regulatory tumor...
4.
Castillo P, Ogando-Rivas E, Geffrard H, Pepe A, Liu R, Nguyen D, et al.
bioRxiv
. 2023 Mar;
PMID: 36993158
To prospectively determine whether brain tumors will respond to immune checkpoint inhibitors (ICIs), we developed a novel mRNA vaccine as a viral mimic to elucidate cytokine release from brain cancer...
5.
Tehrani N, Amirghofran Z, Shamsaeefar A, Karachi A, Karimi M
Galen Med J
. 2021 Sep;
9:e1730.
PMID: 34466580
Background: It has been well-documented that the Fc receptor-like (FCRL) molecule contributes to the pathogenesis of certain autoimmune disorders. FCRL molecules belong to the immunoglobulin superfamily produced by B cells....
6.
Karachi A, Dastmalchi F, Nazarian S, Huang J, Sayour E, Jin L, et al.
Front Immunol
. 2021 Aug;
12:705580.
PMID: 34421912
Evading T cell surveillance is a hallmark of cancer. Patients with solid tissue malignancy, such as glioblastoma (GBM), have multiple forms of immune dysfunction, including defective T cell function. T...
7.
Dastmalchi F, Deleyrolle L, Karachi A, Mitchell D, Rahman M
Front Oncol
. 2021 Jun;
11:691246.
PMID: 34150663
Immunotherapy has revolutionized care for many solid tissue malignancies, and is being investigated for efficacy in the treatment of malignant brain tumors. Identifying a non-invasive monitoring technique such as metabolomics...
8.
Rahman M, Sawyer W, Lindhorst S, Deleyrolle L, Harrison J, Karachi A, et al.
Neuro Oncol
. 2020 May;
22(9):1249-1261.
PMID: 32391559
In oncology, "immunotherapy" is a broad term encompassing multiple means of utilizing the patient's immune system to combat malignancy. Prominent among these are immune checkpoint inhibitors, cellular therapies including chimeric...
9.
Vlasak A, Shin D, Kubilis P, Roper S, Karachi A, Hoh B, et al.
World Neurosurg
. 2019 Dec;
135:e510-e519.
PMID: 31863896
Background: Patient safety indicators (PSIs) and hospital-acquired conditions (HACs) are reported quality measures. We compared their prevalence in patients with secretory and nonsecretory pituitary adenoma using the National (Nationwide) Inpatient...
10.
Dastmalchi F, Karachi A, Yang C, Azari H, Sayour E, Dechkovskaia A, et al.
J Immunother Cancer
. 2019 Nov;
7(1):321.
PMID: 31753028
Background: Dendritic cell (DC) vaccine efficacy is directly related to the efficiency of DC migration to the lymph node after delivery to the patient. We discovered that a naturally occurring...