Aiai Gao
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Explore the profile of Aiai Gao including associated specialties, affiliations and a list of published articles.
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15
Citations
191
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Recent Articles
1.
Qiu T, Wei S, Fang K, Zhang M, Li Y, Feng Y, et al.
Sci Adv
. 2024 Aug;
10(34):eadp0345.
PMID: 39178266
The regulation of leaf senescence and disease resistance plays a crucial role in determining rice grain yield and quality, which are important to meet the ever-increasing food demands of the...
2.
Liu F, Gao A, Zhang M, Li Y, Zhang F, Herman J, et al.
J Transl Int Med
. 2024 Jul;
12(3):274-287.
PMID: 39081276
Background And Objectives: Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest malignancies. An epigenetic-based synthetic lethal strategy provides a novel opportunity for PDAC treatment. Finding more DNA damage repair...
3.
Zhou J, Zhang M, Gao A, Herman J, Guo M
Epigenomics
. 2024 Jul;
16(13):929-944.
PMID: 39023358
The aim of current study is to explore the epigenetic changes and function of KCTD8 in human hepatocellular carcinoma (HCC). HCC cell lines and tissue samples were employed. Methylation specific...
4.
Yao Y, Lv H, Zhang M, Li Y, Herman J, Brock M, et al.
Front Med
. 2024 Jun;
18(4):721-734.
PMID: 38926248
Synthetic lethality is a novel model for cancer therapy. To understand the function and mechanism of BEN domain-containing protein 4 (BEND4) in pancreatic cancer, eight cell lines and a total...
5.
Zhang M, Li X, Herman J, Gao A, Wang Q, Yao Y, et al.
Clin Transl Gastroenterol
. 2024 Jan;
15(3):e00682.
PMID: 38235705
Introduction: The aim of this study was to investigate the epigenetic regulation and underlying mechanism of NRIP3 in colorectal cancer (CRC). Methods: Eight cell lines (SW480, SW620, DKO, LOVO, HT29,...
6.
Du Q, Zhang M, Gao A, He T, Guo M
Cancer Biol Ther
. 2024 Jan;
25(1):2302924.
PMID: 38226836
Pancreatic ductal adenocarcinoma (PDAC) is the most malignant tumor. Zinc finger and SCAN domain-containing protein 23 () is a new member of the SCAN domain family. The expression regulation and...
7.
Gao A, Bai P, Zhang M, Yao Y, Herman J, Guo M
Epigenomics
. 2023 Dec;
15(22):1205-1220.
PMID: 38093706
The mechanism of RASSF1A in DNA damage repair remains to be further clarified for applying to synthetic lethal strategy. Eight esophageal cancer cell lines, 181 cases of esophageal dysplasia and...
8.
Du W, Gao A, Herman J, Wang L, Zhang L, Jiao S, et al.
Cancer Sci
. 2021 May;
112(7):2870-2883.
PMID: 33931924
Wnt, PI3K-Akt-mTOR, and NF-κB pathways were reported to be involved in DNA damage repair (DDR). DDR-deficient cancers become critically dependent on backup DNA repair pathways. Neuritin 1 (NRN1) is reported...
9.
Gao A, Guo M
Biomark Res
. 2020 Sep;
8:44.
PMID: 32974031
Over the past decades, it is recognized that loss of DNA damage repair (DDR) pathways is an early and frequent event in tumorigenesis, occurring in 40-50% of many cancer types....
10.
Ma Y, He S, Gao A, Zhang Y, Zhu Q, Wang P, et al.
Clin Epigenetics
. 2020 Feb;
12(1):25.
PMID: 32046777
Background: Although massive studies have been conducted to investigate the mechanisms of esophageal squamous cell carcinoma (ESCC) carcinogenesis, the understanding of molecular alterations during the malignant transformation of epithelial dysplasia...