Ai Orimoto
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Explore the profile of Ai Orimoto including associated specialties, affiliations and a list of published articles.
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21
Citations
83
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Recent Articles
1.
Orimoto A, Wang Z, Ono M, Kitamura C, Ono K
J Oral Biosci
. 2024 Dec;
:100603.
PMID: 39710093
Objectives: Dental pulp stem cells (DPSCs) are essential for reparative dentinogenesis following damage or infection. DPSCs surrounding the blood vessels in the central region of the dental pulp actively proliferate...
2.
Orimoto A, Kashiwagi S, Funakoshi A, Shimizu T, Ishii T, Kiyono T, et al.
Cell Biol Int
. 2024 Jul;
48(10):1573-1587.
PMID: 38961533
The senescence-associated protein p16 acts as a limiter element in cell-cycle progression. The loss of p16 function is causally related to cellular immortalization. The increase in p16 levels with advancing...
3.
Orimoto A, Addison W, Mochizuki S, Ariyoshi W, Ono K, Kitamura C, et al.
Cell Biochem Funct
. 2024 May;
42(4):e4064.
PMID: 38807466
Human dental pulp stem cells are a potentially useful resource for cell-based therapies and tissue repair in dental and medical applications. However, the primary culture of isolated dental pulp stem...
4.
Orimoto A, Kitamura C, Ono K
Cell Biol Int
. 2024 Jan;
48(3):369-377.
PMID: 38225667
Dental pulp cells play a crucial role in maintaining the balance of the pulp tissue. They actively respond to bacterial inflammation by producing proinflammatory cytokines, particularly interleukin-6 (IL-6). While many...
5.
Horie S, Nakatomi C, Ito-Sago M, Morii A, Orimoto A, Ikeda H, et al.
Eur J Orthod
. 2023 Aug;
45(5):565-574.
PMID: 37632763
Objectives: Orthodontic mechanical force on the periodontal ligament induces extracellular adenosine triphosphate (ATP) release. However, mechanosensitive molecules have not been confirmed functionally in periodontal ligament cells. In the present study,...
6.
Orimoto A, Kitamura C, Ono K
Sci Rep
. 2022 Jul;
12(1):12343.
PMID: 35853988
Extracellular ATP (adenosine triphosphate) and transient receptor potential ankyrin 1 (TRPA1) channels are involved in calcium signaling in odontoblasts and dental pain. The resin monomer 2-hydroxyethyl methacrylate (HEMA), used in...
7.
Orimoto A, Shinohara H, Eitsuka T, Nakagawa K, Sasaki E, Kiyono T, et al.
Tissue Cell
. 2022 Jun;
77:101848.
PMID: 35714414
Common marmosets are non-human primate models used in biomedical research and genome editing technology. This study aimed to establish cell lines from common marmosets and evaluate their characteristics. We obtained...
8.
Transcriptome analysis to identify the downstream genes of androgen receptor in dermal papilla cells
Furuya K, Fujibayashi S, Wu T, Takahashi K, Takase S, Orimoto A, et al.
BMC Genom Data
. 2022 Jan;
23(1):2.
PMID: 34983378
Background: Testosterone signaling mediates various diseases, such as androgenetic alopecia and prostate cancer. Testosterone signaling is mediated by the androgen receptor (AR). In this study, we fortuitously found that primary...
9.
Orimoto A, Takahashi K, Imai M, Kiyono T, Kawaoka Y, Fukuda T
Cytotechnology
. 2021 Aug;
73(4):555-569.
PMID: 34349346
Supplementary Information: The online version contains supplementary material available at 10.1007/s10616-021-00477-0.
10.
Furuya K, Wu T, Orimoto A, Sugano E, Tomita H, Kiyono T, et al.
Sci Data
. 2021 May;
8(1):126.
PMID: 33963195
Cellular immortalization enables indefinite expansion of cultured cells. However, the process of cell immortalization sometimes changes the original nature of primary cells. In this study, we performed expression profiling of...