Ahmed Aburima
Overview
Explore the profile of Ahmed Aburima including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
377
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Recent Articles
1.
Sennett C, Jia W, Khalil J, Hindle M, Coupland C, Calaminus S, et al.
Cells
. 2025 Jan;
13(24.
PMID: 39768180
Granule secretion is an essential platelet function that contributes not only to haemostasis but also to wound healing, inflammation, and atherosclerosis. Granule secretion from platelets is facilitated, at least in...
2.
Aburima A, Berger M, Spurgeon B, Webb B, Wraith K, Febbraio M, et al.
Blood
. 2021 Feb;
137(5):678-689.
PMID: 33538796
Thrombospondin-1 (TSP-1) is released by platelets upon activation and can increase platelet activation, but its role in hemostasis in vivo is unclear. We show that TSP-1 is a critical mediator...
3.
Kahal H, Halama A, Aburima A, Bhagwat A, Butler A, Graumann J, et al.
Sci Rep
. 2020 Jun;
10(1):10233.
PMID: 32561766
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
4.
Kahal H, Halama A, Aburima A, Bhagwat A, Butler A, Graumann J, et al.
Sci Rep
. 2020 Mar;
10(1):4750.
PMID: 32179763
Intensive diabetes control has been associated with increased mortality in type 2 diabetes (T2DM); this has been suggested to be due to increased hypoglycemia. We measured hypoglycemia-induced changes in endothelial...
5.
Berger M, Raslan Z, Aburima A, Magwenzi S, Wraith K, Spurgeon B, et al.
Haematologica
. 2019 Jul;
105(3):808-819.
PMID: 31289200
Prostacyclin (PGI) controls platelet activation and thrombosis through a cyclic adenosine monophosphate (cAMP) signaling cascade. However, in patients with cardiovascular diseases this protective mechanism fails for reasons that are unclear....
6.
Berger M, Lutz D, Lutz J, Khalil J, Aburima A, Naseem K, et al.
Cells
. 2019 Feb;
8(2).
PMID: 30754723
Typical Rho GTPases, such as Rac1, Cdc42, and RhoA, act as molecular switches regulating various aspects of platelet cytoskeleton reorganization. The loss of these enzymes results in reduced platelet functionality....
7.
Sfyri P, Yuldasheva N, Tzimou A, Giallourou N, Crispi V, Aburima A, et al.
Free Radic Biol Med
. 2018 Oct;
129:504-519.
PMID: 30342191
Obesity leading to hyperlipidaemia and atherosclerosis is recognised to induce morphological and metabolic changes in many tissues. However, hyperlipidaemia can occur in the absence of obesity. The impact of the...
8.
Scully D, Sfyri P, Verpoorten S, Papadopoulos P, Munoz-Turrillas M, Mitchell R, et al.
Acta Physiol (Oxf)
. 2018 Oct;
225(3):e13207.
PMID: 30339324
Aim: The use of platelets as biomaterials has gained intense research interest. However, the mechanisms regarding platelet-mediated skeletal myogenesis remain to be established. The aim of this study was to...
9.
Berger M, Wraith K, Woodward C, Aburima A, Raslan Z, Hindle M, et al.
Platelets
. 2018 May;
30(4):467-472.
PMID: 29733744
Oxidized low-density lipoprotein (oxLDL) and associated oxidized phosphocholine-headgroup phospholipids (oxPCs) activate blood platelets through ligation of the scavenger receptor CD36. Previously, we found that oxLDL stimulated phosphorylation of phospholipase Cγ2...
10.
Raslan Z, Aburima A, Naseem K
Front Pharmacol
. 2015 Dec;
6:266.
PMID: 26617518
Atherothrombosis, the pathology underlying numerous cardiovascular diseases, is a major cause of death globally. Hyperactive blood platelets play a key role in the atherothrombotic process through the release of inflammatory...