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Ahmad Gebai

Explore the profile of Ahmad Gebai including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 72
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Recent Articles
1.
Desilets A, Elkhoury R, Gebai A, Tehfe M
Curr Oncol . 2023 Oct; 30(10):9304-9316. PMID: 37887572
Gastric cancer is the fifth most common malignancy worldwide and one of the main causes of cancer-related death. While surgical treatment is the only curative option for early disease, many...
2.
Sene P, Gebai A, Kopel T, Cailhier J, Lafrance D, Cote J
BMC Nephrol . 2023 Sep; 24(1):257. PMID: 37658303
Background: Delayed cerebral ischemia is a clinical entity commonly encountered in patients presenting with acute neurological injury and is often complicated by dysnatremias, such as the cerebral salt wasting syndrome....
3.
Gorelik A, Gebai A, Illes K, Piomelli D, Nagar B
Proc Natl Acad Sci U S A . 2018 Oct; 115(43):E10032-E10040. PMID: 30301806
Palmitoylethanolamide is a bioactive lipid that strongly alleviates pain and inflammation in animal models and in humans. Its signaling activity is terminated through degradation by -acylethanolamine acid amidase (NAAA), a...
4.
Gebai A, Gorelik A, Nagar B
J Struct Biol . 2018 Jul; 204(2):145-150. PMID: 30026085
Saposins are accessory proteins that aid in the degradation of sphingolipids by hydrolytic enzymes. Their structure usually comprises four α-helices arranged in various conformations including an open, V-shaped form that...
5.
Gebai A, Gorelik A, Li Z, Illes K, Nagar B
Nat Commun . 2018 Apr; 9(1):1621. PMID: 29692406
Acid ceramidase (aCDase, ASAH1) hydrolyzes lysosomal membrane ceramide into sphingosine, the backbone of all sphingolipids, to regulate many cellular processes. Abnormal function of aCDase leads to Farber disease, spinal muscular...