Author: Agustin Albillos

1.

Gene score to quantify systemic inflammation in patients with acutely decompensated cirrhosis

Trebicka J, Aguilar F, Farias A, Lozano J, Sanchez-Garrido C, Uson-Raposo E, et al.

Gut . 2025 Feb; PMID: 40011033

Background And Aims: Quantifying systemic inflammation (SI) in acutely decompensated cirrhosis (ADC) is of major importance because SI is a driver of the most severe forms of ADC, including acute-on-chronic...

2.

Progressive systemic inflammation precedes decompensation in compensated cirrhosis

Sanchez-Aldehuelo R, Villanueva C, Genesca J, Garcia-Pagan J, Castillo E, Calleja J, et al.

JHEP Rep . 2025 Jan; 7(2):101231. PMID: 39850960

Background & Aims: Systemic inflammation is a driver of decompensation in cirrhosis with unclear relevance in the compensated stage. We evaluated inflammation and bacterial translocation markers in compensated cirrhosis and...

3.

Portal hypertension: recommendations for diagnosis and treatment. Consensus document sponsored by the Spanish Association for the Study of the Liver (AEEH) and the Biomedical Research Network Centre for Liver and Digestive Diseases (CIBERehd)

Albillos A, Banares R, Hernandez-Gea V

Gastroenterol Hepatol . 2025 Jan; 48(1):502208. PMID: 39756832

Portal hypertension is a hemodynamic abnormality that complicates the course of cirrhosis, as well as other diseases that affect the portal venous circulation. The development of portal hypertension compromises prognosis,...

4.

Endoscopic sleeve gastroplasty plus lifestyle intervention in patients with MASH: a multicentre, sham-controlled, randomized trial

Abad J, Llop E, Arias-Loste M, Burgos-Santamaria D, Martinez Porras J, Iruzubieta P, et al.

Clin Gastroenterol Hepatol . 2024 Dec; PMID: 39694202

Metabolic dysfunction-associated steatohepatitis(MASH) is commonly seen in biopsy proven steatotic liver disease(SLD). Life-style intervention reaching a weight loss higher than 10% promotes MASH resolution, but this goal is only achieved...

5.

Utility of endoscopic ultrasound-guided fine needle aspiration for genetic analysis in pancreatic ductal adenocarcinoma

Ligato I, Garcia Garcia de Paredes A, Duran S, Gonzalez Garcia I, Benito Berlinches A, Romio de Las Heras E, et al.

HPB (Oxford) . 2024 Dec; 27(3):414-416. PMID: 39674743

No abstract available.

6.

Improving understanding of ferroptosis: Molecular mechanisms, connection with cellular senescence and implications for aging

De Leon-Oliva D, Boaru D, Minaya-Bravo A, De Castro-Martinez P, Fraile-Martinez O, Garcia-Montero C, et al.

Heliyon . 2024 Nov; 10(21):e39684. PMID: 39553553

In the face of cell damage, cells can initiate a response ranging from survival to death, the balance being crucial for tissue homeostasis and overall health. Cell death, in both...

7.

Harnessing the Anti-Inflammatory Properties of Polyphenols in the Treatment of Inflammatory Bowel Disease

Boaru D, Fraile-Martinez O, De Leon-Oliva D, Garcia-Montero C, De Castro-Martinez P, Miranda-Gonzalez A, et al.

Int J Biol Sci . 2024 Nov; 20(14):5608-5672. PMID: 39494333

Inflammatory bowel disease (IBD) encompasses a spectrum of chronic inflammatory conditions affecting the gastrointestinal tract, notably ulcerative colitis (UC) and Crohn's disease (CD). Both UC and CD result from the...

8.

Endoscopic ultrasound-guided choledochoduodenostomy (EUS-CDS) as first-line treatment for malignant distal biliary obstruction

Alvarez Varela C, Olcina J, Lopez-Duran S, Garcia Garcia de Paredes A, Tavio E, Meruendano Padron C, et al.

Rev Esp Enferm Dig . 2024 Oct; PMID: 39421918

In patients with malignant distal biliary obstruction, drainage via Endoscopic Ultrasound-guided Choledochoduodenostomy (EUS-CDS) is indicated in clinical guidelines following a failed Endoscopic Retrograde Cholangiopancreatography (ERCP). However, current interest lies in...

9.

Portal hypertension: recommendations for diagnosis and treatment. Consensus document sponsored by the Spanish Association for the Study of the Liver (AEEH) and the Biomedical Research Network Center for Liver and Digestive Diseases (CIBERehd)

Albillos A, Banares R, Hernandez-Gea V

Rev Esp Enferm Dig . 2024 Oct; 117(1):14-57. PMID: 39350672

Portal hypertension is a hemodynamic abnormality that complicates the course of cirrhosis, as well as other diseases that affect the portal venous circulation. The development of portal hypertension compromises prognosis,...

10.

Spleen stiffness measurement by vibration-controlled transient elastography at 100 Hz for non-invasive predicted diagnosis of clinically significant portal hypertension in patients with compensated advanced chronic liver disease: a modelling study

Jachs M, Odriozola A, Turon F, Moga L, Tellez L, Fischer P, et al.

Lancet Gastroenterol Hepatol . 2024 Sep; 9(12):1111-1120. PMID: 39326431

Background: In patients with compensated advanced chronic liver disease (cACLD), risk of clinically significant portal hypertension (CSPH) can be estimated by applying non-invasive tests such as liver stiffness measurement (LSM),...