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Agnieszka Malcher

Explore the profile of Agnieszka Malcher including associated specialties, affiliations and a list of published articles. Areas
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Articles 30
Citations 253
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Recent Articles
1.
Budzinska M, Malcher A, Zimna A, Kurpisz M
Int J Mol Sci . 2024 Nov; 25(22). PMID: 39595938
Duchenne Muscular Dystrophy (DMD) is a genetic disorder characterized by disruptions in the dystrophin gene. This study aims to investigate potential a therapeutic approach using genetically modified human iPS-derived mesoangioblast-like...
2.
Malcher A, Kamieniczna M, Rozwadowska N, Stokowy T, Berger A, Jedrzejczak P, et al.
Reprod Biol . 2024 Sep; 24(4):100949. PMID: 39236514
The gonadotropin treatment of infertile men may improve spermatogenesis and lead to sperm cell production, however, only a small fraction of treated patients positively responds to such therapy. To identify...
3.
Kamieniczna M, Olszewska M, Malcher A, Stokowy T, Gunes S
Front Genet . 2024 Jul; 15:1432026. PMID: 38988834
No abstract available.
4.
Olszewska M, Malcher A, Stokowy T, Pollock N, Berman A, Budkiewicz S, et al.
Hum Reprod Open . 2024 Apr; 2024(2):hoae020. PMID: 38650655
Study Question: Is the mutation causative for male infertility? Summary Answer: Our collected data underline the complex and devastating effect of the single-gene mutation on the testicular molecular network, leading...
5.
Malcher A, Graczyk Z, Bauer H, Stokowy T, Berman A, Smolibowski M, et al.
Sci Rep . 2023 Oct; 13(1):16563. PMID: 37783880
Infertility is a problem that affects approximately 15% of couples, and male infertility is responsible for 40-50% of these cases. The cause of male infertility is still poorly diagnosed and...
6.
Qureshi S, Hardy J, Pombar C, Berman A, Malcher A, Gingrich T, et al.
Front Genet . 2023 May; 14:1134849. PMID: 37234866
Human spermatogenesis is a highly intricate process that requires the input of thousands of testis-specific genes. Defects in any of them at any stage of the process can have detrimental...
7.
Malcher A, Stokowy T, Berman A, Olszewska M, Jedrzejczak P, Sielski D, et al.
Andrology . 2022 Aug; 10(8):1605-1624. PMID: 36017582
Background: Genetic causes that lead to spermatogenetic failure in patients with nonobstructive azoospermia (NOA) have not been yet completely established. Objective: To identify low-frequency NOA-associated single nucleotide variants (SNVs) using...
8.
Nowaczyk M, Malcher A, Zimna A, Rozwadowska N, Kurpisz M
Kardiol Pol . 2022 May; 80(7-8):813-824. PMID: 35554929
Background: The application of a circulating miR-195 inhibitor could be a helping factor in the in vitro model of human skeletal muscle-derived stem/progenitor cells (SkMDS/PCs). Previously, microRNA-195 (miR-195) expression has...
9.
Nowicka-Bauer K, Malcher A, Wloczkowska O, Kamieniczna M, Olszewska M, Kurpisz M
Reprod Biol . 2021 Dec; 22(1):100597. PMID: 34959194
In mammals, testicular Heat shock-related 70 kDa protein 2 (HSPA2) is a chaperon strictly linked to spermatogenesis status, whereas its presence in spermatozoa ensures successful oocyte fertilization. However, there is...
10.
Nowaczyk M, Malcher A, Zimna A, Labedz W, Kubaszewski L, Barczak W, et al.
Antioxidants (Basel) . 2021 Jul; 10(6). PMID: 34203726
The aim of the study was to modify human skeletal muscle-derived stem/progenitor cells (SkMDS/PCs) and demonstrate the optimal cell preparation protocol for application in post-infarction hearts. We used conditioned SkMDS/PC...