Agnieszka Krawczyk-Lebek
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Explore the profile of Agnieszka Krawczyk-Lebek including associated specialties, affiliations and a list of published articles.
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13
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70
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Recent Articles
1.
Jaworska D, Klosek M, Bronikowska J, Krawczyk-Lebek A, Perz M, Kostrzewa-Suslow E, et al.
Int J Mol Sci
. 2025 Jan;
26(2).
PMID: 39859444
Flavones are natural compounds that are broadly distributed in our diet. Their unique properties provide the possibility to control the immune system and the process of inflammation. A high intake...
2.
Krawczyk-Lebek A, Zarowska B, Janeczko T, Kostrzewa-Suslow E
Int J Mol Sci
. 2024 Sep;
25(17).
PMID: 39273666
Chalcones, secondary plant metabolites, exhibit various biological properties. The introduction of a chlorine and a glucosyl substituent to the chalcone could enhance its bioactivity and bioavailability. Such compounds can be...
3.
Krawczyk-Lebek A, Zarowska B, Dymarska M, Janeczko T, Kostrzewa-Suslow E
Sci Rep
. 2024 Jul;
14(1):15050.
PMID: 38951205
Chalcones are intermediate products in the biosynthesis of flavonoids, which possess a wide range of biological properties, including antimicrobial and anticancer activities. The introduction of a chlorine atom and the...
4.
Cyboran-Mikolajczyk S, Matczak K, Olchowik-Grabarek E, Sekowski S, Nowicka P, Krawczyk-Lebek A, et al.
Chem Biol Interact
. 2024 Jun;
398:111082.
PMID: 38825055
The study investigates the effect of the presence of a chlorine atom in the 2'-hydroxychalcone molecule on its interaction with model lipid membranes, in order to discern its potential pharmacological...
5.
Klosek M, Kurek-Gorecka A, Balwierz R, Krawczyk-Lebek A, Kostrzewa-Suslow E, Bronikowska J, et al.
Molecules
. 2024 May;
29(10).
PMID: 38792101
Chemokines, also known as chemotactic cytokines, stimulate the migration of immune cells. These molecules play a key role in the pathogenesis of inflammation leading to atherosclerosis, neurodegenerative disorders, rheumatoid arthritis,...
6.
Dudek A, Szulc N, Pawlak A, Strugala-Danak P, Krawczyk-Lebek A, Perz M, et al.
Sci Rep
. 2024 May;
14(1):10561.
PMID: 38719884
This study focuses on understanding the structural and molecular changes in lipid membranes under the influence of six halogenated flavonoid derivatives differing in the number and position of substitution of...
7.
Klosek M, Krawczyk-Lebek A, Kostrzewa-Suslow E, Szliszka E, Bronikowska J, Jaworska D, et al.
Molecules
. 2023 Dec;
28(23).
PMID: 38067567
Inflammation plays an important role in the immune defense against injury and infection agents. However, the inflammatory chronic process may lead to neurodegenerative diseases, atherosclerosis, inflammatory bowel diseases, or cancer....
8.
Perz M, Krawczyk-Lebek A, Dymarska M, Janeczko T, Kostrzewa-Suslow E
Int J Mol Sci
. 2023 Jun;
24(11).
PMID: 37298456
Combining chemical and microbiological methods using entomopathogenic filamentous fungi makes obtaining flavonoid glycosides possible. In the presented study, biotransformations were carried out in cultures of KCH J1.5, KCH J2, and...
9.
Cyboran-Mikolajczyk S, Bonarska-Kujawa D, Meczarska K, Krawczyk-Lebek A, Kostrzewa-Suslow E
Membranes (Basel)
. 2022 Oct;
12(10).
PMID: 36295737
Flavonoids were biotransformed using various microorganisms, in order to obtain new compounds with potentially high biological activity. The aim of this work was to determine and compare the biological activity...
10.
Krawczyk-Lebek A, Dymarska M, Janeczko T, Kostrzewa-Suslow E
Int J Mol Sci
. 2022 May;
23(10).
PMID: 35628367
Flavonoid compounds are secondary plant metabolites with numerous biological activities; they naturally occur mainly in the form of glycosides. The glucosyl moiety attached to the flavonoid core makes them more...