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Agnieszka K Bronowska

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Articles 26
Citations 445
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Recent Articles
1.
Abdelghany T, Bosak J, Leitch A, Charlton A, Fan L, Aljehani F, et al.
Chemosphere . 2025 Feb; 374:144213. PMID: 39970765
Methylimidazolium ionic liquids (MILs) are solvents used in an increasing variety of industrial applications. Recent studies identified the 8C MIL (M8OI) contaminating the environment, detected exposure in humans and proposed...
2.
Arrowsmith T, Xu X, Xu S, Usher B, Stokes P, Guest M, et al.
Nat Commun . 2024 Sep; 15(1):7719. PMID: 39231966
Nucleotidyltransferases (NTases) control diverse physiological processes, including RNA modification, DNA replication and repair, and antibiotic resistance. The Mycobacterium tuberculosis NTase toxin family, MenT, modifies tRNAs to block translation. MenT toxin...
3.
Abdelghany T, Hedya S, Charlton A, Fan L, Fazili N, Air B, et al.
Chemosphere . 2024 Jul; 363:142827. PMID: 39019179
A class of chemical with a potentially important perceived future contribution to the net zero carbon goal (as "green" solvents) is the methylimidazolium ionic liquids (MILs). These solvents are used...
4.
Stennett A, Friston K, Harris C, Wollman A, Bronowska A, Madden K
Expert Opin Ther Targets . 2023 Feb; 27(2):97-109. PMID: 36786123
Introduction: Complement-based drug discovery is undergoing a renaissance, empowered by new advances in structural biology, complement biology and drug development. Certain components of the complement pathway, particularly C1q and C3,...
5.
Xu S, Kondal M, Ahmad A, Zhu R, Fan L, Zaborniak P, et al.
Int J Mol Sci . 2023 Jan; 24(2). PMID: 36674785
The androgen receptor (AR) is an important drug target in prostate cancer and a driver of castration-resistant prostate cancer (CRPC). A significant challenge in designing effective drugs lies in targeting...
6.
Kataura T, Otten E, Rabanal-Ruiz Y, Adriaenssens E, Urselli F, Scialo F, et al.
EMBO J . 2022 Dec; 42(5):e111372. PMID: 36514953
Mitophagy, the elimination of mitochondria via the autophagy-lysosome pathway, is essential for the maintenance of cellular homeostasis. The best characterised mitophagy pathway is mediated by stabilisation of the protein kinase...
7.
Duchemin N, Aubert S, de Souza J, Bethge L, Vonhoff S, Bronowska A, et al.
JACS Au . 2022 Aug; 2(8):1910-1917. PMID: 36032523
By harnessing the chirality of the DNA double helix, chemists have been able to obtain new, reliable, selective, and environmentally friendly biohybrid catalytic systems with tailor-made functions. Nonetheless, despite all...
8.
Al-Khawaldeh I, Al Yasiri M, Aldred G, Basmadjian C, Bordoni C, Harnor S, et al.
J Med Chem . 2021 Jul; 64(14):10001-10018. PMID: 34212719
NF-κB-inducing kinase (NIK) is a key enzyme in the noncanonical NF-κB pathway, of interest in the treatment of a variety of diseases including cancer. Validation of NIK as a drug...
9.
Liu D, de Souza J, Ahmad A, Bronowska A
Int J Mol Sci . 2021 Jun; 22(11). PMID: 34067314
Cholinergic α7 nicotinic receptors encoded by the gene are ligand-gated ion channels directly related to memory and immunomodulation. Exons 5-7 in can be duplicated and fused to exons A-E of...
10.
de Souza J, Kondal M, Zaborniak P, Cairns R, Bronowska A
Int J Mol Sci . 2021 Mar; 22(4). PMID: 33670396
Phytosulfokine (PSK) is a phytohormone responsible for cell-to-cell communication in plants, playing a pivotal role in plant development and growth. The binding of PSK to its cognate receptor, PSKR1, is...