Agnieszka Cios
Overview
Explore the profile of Agnieszka Cios including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
14
Citations
66
Followers
0
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Recent Articles
1.
Jastrzebska-Wiesek M, Garbo S, Cios A, Wilczynska-Zawal N, Partyka A, Honkisz-Orzechowska E, et al.
ACS Chem Neurosci
. 2025 Feb;
PMID: 40020084
Among serotonin receptors, the 5-HT subtype is an important protein target and its ligands may play a key role in the innovative treatment of cognitive disorders. This study aimed to...
2.
Wiesner A, Zagrodzki P, Gawalska A, Marcinkowska M, Cios A, Pasko P
Eur J Pharm Biopharm
. 2025 Jan;
208:114652.
PMID: 39875059
Background: Given the challenges of pediatric antibacterial therapy, it is crucial to formulate antibiotics with a lower potential for interaction with dietary interventions and tailor them for optimal administration in...
3.
Cios A, Chlon-Rzepa G, Jastrzebska-Wiesek M, Pociecha K, Wojcik-Pszczola K, Pekala E, et al.
Pharmacol Rep
. 2024 Dec;
77(1):158-171.
PMID: 39676141
Background: Research on new candidates for antidepressant/anxiolytic drugs from the long-chain arylpiperazines (LCAPs) group containing a 1,3-dimethylpurine-2,6-dione as a terminal amide fragment fits into the modern exploration trend. This study...
4.
Swierczek A, Szafarz M, Cios A, Kobierski J, Pociecha K, Attard Saliba D, et al.
Pharmaceutics
. 2024 Nov;
16(11).
PMID: 39598586
Objective: The aim of this study was to develop quantitative structure-pharmacokinetics relationship (QSPKR) models for a group of xanthine derivatives with proven pharmacological activity and to investigate its applicability for...
5.
Pyka P, Haberek W, Wiecek M, Szymanska E, Ali W, Cios A, et al.
J Med Chem
. 2024 Jan;
67(2):1580-1610.
PMID: 38190615
Alzheimer's disease (AD) has a complex and not-fully-understood etiology. Recently, the serotonin receptor 5-HT emerged as a promising target for AD treatment; thus, here a new series of 5-HTR ligands...
6.
Waszkielewicz A, Marona H, Panczyk-Straszak K, Filipek B, Rapacz A, Salat K, et al.
Pharmacol Rep
. 2022 Nov;
75(1):128-165.
PMID: 36401763
Background: Epilepsy frequently coexists with neuropathic pain. Our approach is based on the search for active compounds with multitarget profiles beneficial in terms of potential side effects and on the...
7.
Sudol S, Cios A, Jastrzebska-Wiesek M, Honkisz-Orzechowska E, Mordyl B, Wilczynska-Zawal N, et al.
Int J Mol Sci
. 2021 Oct;
22(19).
PMID: 34639113
Among the serotonin receptors, one of the most recently discovered 5-HT subtype is an important protein target and its ligands may play a key role in the innovative treatment of...
8.
Marcinkowska M, Bucki A, Sniecikowska J, Zagorska A, Fajkis-Zajaczkowska N, Siwek A, et al.
J Med Chem
. 2021 Aug;
64(17):12603-12629.
PMID: 34436892
The current pharmaceutical market lacks therapeutic agents designed to modulate behavioral disturbances associated with dementia. To address this unmet medical need, we designed multifunctional ligands characterized by a nanomolar affinity...
9.
Kubacka M, Rapacz A, Salat K, Filipek B, Cios A, Pociecha K, et al.
Eur J Pharmacol
. 2020 Sep;
886:173540.
PMID: 32896552
Anticonvulsant drugs are used to treat a wide range of non-epileptic conditions, including chronic, neuropathic pain. We obtained a phenoxyalkylaminoalkanol derivative, KM-416 which had previously demonstrated a significant anticonvulsant activity...
10.
Wesolowska A, Jastrzebska-Wiesek M, Cios A, Partyka A
Expert Opin Drug Discov
. 2019 Oct;
15(3):279-292.
PMID: 31661992
: Paliperidone is approved in the United States and Europe for the short- and long-term treatment of schizophrenia in adults and adolescents as well as for the acute treatment of...