Agnes A Steixner-Kumar
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Explore the profile of Agnes A Steixner-Kumar including associated specialties, affiliations and a list of published articles.
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16
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1057
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Recent Articles
1.
Sauer J, Steixner-Kumar A, Gabler S, Motyka M, Rippmann J, Brosa S, et al.
Front Immunol
. 2024 Apr;
15:1232070.
PMID: 38638443
Chronic liver diseases, such as non-alcoholic steatohepatitis (NASH)-induced cirrhosis, are characterized by an increasing accumulation of stressed, damaged, or dying hepatocytes. Hepatocyte damage triggers the activation of resident immune cells,...
2.
Jones A, Bajrami B, Campbell M, Erzurumluoglu A, Guo Q, Chen H, et al.
Hepatol Commun
. 2024 Apr;
8(5).
PMID: 38619429
Background: Mutations in the gene MTARC1 (mitochondrial amidoxime-reducing component 1) protect carriers from metabolic dysfunction-associated steatohepatitis (MASH) and cirrhosis. MTARC1 encodes the mARC1 enzyme, which is localized to the mitochondria...
3.
Bahrami E, Geiger T, Steixner-Kumar A, Santacruz D, Viollet C, Dick A, et al.
STAR Protoc
. 2023 Sep;
4(4):102597.
PMID: 37740914
Immune dysregulation and inflammation by hepatic-resident leukocytes is considered a key step in disease progression of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis toward cirrhosis and hepatocellular carcinoma. Here, we...
4.
Depp C, Sun T, Sasmita A, Spieth L, Berghoff S, Nazarenko T, et al.
Nature
. 2023 May;
618(7964):349-357.
PMID: 37258678
The incidence of Alzheimer's disease (AD), the leading cause of dementia, increases rapidly with age, but why age constitutes the main risk factor is still poorly understood. Brain ageing affects...
5.
Ehrenreich H, Garcia-Agudo L, Steixner-Kumar A, Wilke J, Butt U
Mol Psychiatry
. 2022 Apr;
27(5):2372-2379.
PMID: 35414656
Executive functions, learning, attention, and processing speed are imperative facets of cognitive performance, affected in neuropsychiatric disorders. In clinical studies on different patient groups, recombinant human (rh) erythropoietin (EPO) lastingly...
6.
Trubetskoy V, Pardinas A, Qi T, Panagiotaropoulou G, Awasthi S, Bigdeli T, et al.
Nature
. 2022 Apr;
604(7906):502-508.
PMID: 35396580
Schizophrenia has a heritability of 60-80%, much of which is attributable to common risk alleles. Here, in a two-stage genome-wide association study of up to 76,755 individuals with schizophrenia and...
7.
Arinrad S, Wilke J, Seelbach A, Doeren J, Hindermann M, Butt U, et al.
Mol Psychiatry
. 2021 Dec;
27(12):4974-4983.
PMID: 34866134
Encephalitis has an estimated prevalence of ≤0.01%. Even with extensive diagnostic work-up, an infectious etiology is identified or suspected in <50% of cases, suggesting a role for etiologically unclear, noninfectious...
8.
Garcia-Agudo L, Steixner-Kumar A, Curto Y, Barnkothe N, Hassouna I, Jahne S, et al.
Cell Rep
. 2021 Aug;
36(8):109548.
PMID: 34433021
In adult cornu ammonis hippocampi, erythropoietin (EPO) expression drives the differentiation of new neurons, independent of DNA synthesis, and increases dendritic spine density. This substantial brain hardware upgrade is part...
9.
Wilke J, Hindermann M, Berghoff S, Zihsler S, Arinrad S, Ronnenberg A, et al.
Mol Psychiatry
. 2021 Jul;
26(12):7746-7759.
PMID: 34331009
The etiology and pathogenesis of "anti-N-methyl-D-aspartate-receptor (NMDAR) encephalitis" and the role of autoantibodies (AB) in this condition are still obscure. While NMDAR1-AB exert NMDAR-antagonistic properties by receptor internalization, no firm...
10.
Deutsch N, Worthmann H, Steixner-Kumar A, Schuppner R, Grosse G, Pan H, et al.
Brain Behav Immun
. 2021 May;
96:73-79.
PMID: 34010714
Background And Purpose: Preexisting autoantibodies against N-methyl-D-aspartate-receptor subunit NR1 (NMDAR1-AB) in acute ischemic stroke patients with previously intact blood-brain-barrier were associated with smaller evolution of lesion size. Effects of chronic...