Afroditi Nanou
Overview
Explore the profile of Afroditi Nanou including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
224
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0
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Recent Articles
1.
Cieslik S, Zafra A, Driemel C, Sudarsanam M, Cieslik J, Flugen G, et al.
J Exp Clin Cancer Res
. 2025 Jan;
44(1):9.
PMID: 39773651
Background: Circulating tumour cells (CTCs) and tumour-derived extracellular vesicles (tdEVs) have great potential for monitoring therapy response and early detection of tumour relapse, facilitating personalized adjuvant therapeutic strategies. However, their...
2.
Nanou A, Stoecklein N, Doerr D, Driemel C, Terstappen L, Coumans F
PNAS Nexus
. 2024 Feb;
3(2):pgae048.
PMID: 38371418
Circulating tumor cell (CTC) and tumor-derived extracellular vesicle (tdEV) loads are prognostic factors of survival in patients with carcinoma. The current method of CTC enumeration relies on operator review and,...
3.
Stevens M, Mentink A, Nanou A, Coumans F, Isebia K, Kraan J, et al.
Cytometry A
. 2023 Jul;
103(11):881-888.
PMID: 37461156
The median number of circulating tumor cells (CTCs) detected in 7.5 mL of peripheral blood by CellSearch (PB-CS) in patients with metastatic prostate cancer is in the order of 1-10,...
4.
Nanou A, Miao J, Coumans F, Dolce E, Darga E, Barlow W, et al.
JCO Precis Oncol
. 2023 Jan;
7():e2200372.
PMID: 36634296
Purpose: Circulating tumor cells (CTCs) are strongly prognostic for overall survival (OS) in metastatic breast cancer although additional prognostic biomarkers are needed. We evaluated the complementary prognostic value of tumor-derived...
5.
Isebia K, Dathathri E, Verschoor N, Nanou A, de Jong A, Coumans F, et al.
Cancers (Basel)
. 2022 Sep;
14(18).
PMID: 36139564
Circulating tumor cell (CTC)- and/or tumor-derived extracellular vesicle (tdEV) loads in the blood of metastatic castration-resistant prostate cancer (CRPC) patients are associated with worse overall survival and can be used...
6.
Stevens M, Nanou A, Terstappen L, Driemel C, Stoecklein N, Coumans F
Cancers (Basel)
. 2022 Jun;
14(12).
PMID: 35740582
After a CellSearch-processed circulating tumor cell (CTC) sample is imaged, a segmentation algorithm selects nucleic acid positive (DAPI+), cytokeratin-phycoerythrin expressing (CK-PE+) events for further review by an operator. Failures in...
7.
Nanou A, Lorenzo-Moldero I, Gazouleas K, Cortese B, Moroni L
ACS Appl Mater Interfaces
. 2022 Jun;
14(24):28389-28402.
PMID: 35687666
Cancer biology research is increasingly moving toward innovative 3D culture models, as conventional and current 2D cell cultures fail to resemble cancer biology. In the current study, porous 3D scaffolds,...
8.
Nanou A, Mol L, Coumans F, Koopman M, Punt C, Terstappen L
Cells
. 2020 Dec;
9(12).
PMID: 33333805
Elevated, tumor-derived extracellular vesicle (tdEV) and circulating tumor cell (CTC) loads in metastatic cancer are associated with poor clinical outcome. Herein, we investigate whether endothelium-derived extracellular vesicles (edEVs) can be...
9.
Nanou A, Zeune L, Bidard F, Pierga J, Terstappen L
Breast Cancer Res
. 2020 Aug;
22(1):86.
PMID: 32787900
Background: Tumor-derived extracellular vesicles (tdEVs) and circulating tumor cells (CTCs) in the blood of metastatic cancer patients associate with poor outcomes. In this study, we explored the human epidermal growth...
10.
Nanou A, Miller M, Zeune L, de Wit S, Punt C, Groen H, et al.
Br J Cancer
. 2020 Jan;
122(6):801-811.
PMID: 31937922
Background: Circulating tumour cells (CTCs) in blood associate with overall survival (OS) of cancer patients, but they are detected in extremely low numbers. Large tumour-derived extracellular vesicles (tdEVs) in castration-resistant...