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Advait V Badkar

Explore the profile of Advait V Badkar including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 185
Followers 0
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Recent Articles
1.
Lewis L, Badkar A, Cirelli D, Combs R, Lerch T
J Pharm Sci . 2022 Sep; 112(3):640-647. PMID: 36130677
At the outset of the coronavirus disease 2019 (COVID-19) pandemic, it was clear that a vaccine would be crucial for global health efforts. The Pfizer and BioNTech teams came together...
2.
Badkar A, Gandhi R, Davis S, LaBarre M
Drug Des Devel Ther . 2021 Jan; 15:159-170. PMID: 33469268
Subcutaneous (SC) delivery of biologics has traditionally been limited to fluid volumes of 1-2 mL, with recent increases to volumes of about 3 mL. This injection volume limitation poses challenges...
3.
Collins D, Sanchez-Felix M, Badkar A, Mrsny R
J Control Release . 2020 Feb; 321:475-482. PMID: 32105759
Subcutaneous (SC) delivery of biotherapeutics is well established as a route of administration across many therapeutic areas and has been shown to be effective and well-tolerated. It can offer several...
4.
Chari R, Jerath K, Badkar A, Kalonia D
Pharm Res . 2009 Oct; 26(12):2607-18. PMID: 19795191
Purpose: To explain the differences in protein-protein interactions (PPI) of concentrated versus dilute formulations of a model antibody. Methods: High frequency rheological measurements from pH 3.0 to 12.0 quantitated viscoelasticity...
5.
Saluja A, Badkar A, Zeng D, Kalonia D
J Pharm Sci . 2007 Jun; 96(12):3181-95. PMID: 17588261
The purpose of this work was to investigate if physical stability of a model monoclonal antibody (IgG(2)), as determined by extent of aggregation, was related to rheology of its solutions....
6.
Badkar A, Smith A, Eppstein J, Banga A
Pharm Res . 2007 Apr; 24(7):1389-95. PMID: 17443396
Purpose: To demonstrate transdermal delivery of interferon alpha-2b (IFNalpha2b) in hairless rats through aqueous microchannels (micropores) created in the skin and enhanced by iontophoresis. Materials And Methods: The Altea Therapeutics...
7.
Saluja A, Badkar A, Zeng D, Nema S, Kalonia D
Biophys J . 2006 Oct; 92(1):234-44. PMID: 17028129
The purpose of this work was to establish ultrasonic storage modulus (G') as a novel parameter for characterizing protein-protein interactions (PPI) in high concentration protein solutions. Using an indigenously developed...
8.
Saluja A, Badkar A, Zeng D, Nema S, Kalonia D
J Pharm Sci . 2006 Jul; 95(9):1967-83. PMID: 16847932
The purpose of this work was to explore the utilization of high-frequency rheology analysis for assessing protein-protein interactions in high protein concentration solutions. Rheology analysis of a model monoclonal immunoglobulin...
9.
Badkar A, Banga A
J Pharm Pharmacol . 2002 Aug; 54(7):907-12. PMID: 12162708
The purpose of this study was to establish the delivery parameters for the enhanced transdermal delivery of dextran sulfate (MW 5000 Da). Full-thickness pig skin or epidermis separated from human...