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Adrien Treuille

Explore the profile of Adrien Treuille including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 1390
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Recent Articles
1.
Wayment-Steele H, Kladwang W, Strom A, Lee J, Treuille A, Becka A, et al.
Nat Methods . 2022 Oct; 19(10):1234-1242. PMID: 36192461
Despite the popularity of computer-aided study and design of RNA molecules, little is known about the accuracy of commonly used structure modeling packages in tasks sensitive to ensemble properties of...
2.
Anderson-Lee J, Fisker E, Kosaraju V, Wu M, Kong J, Lee J, et al.
J Mol Biol . 2016 Feb; 428(5 Pt A):748-757. PMID: 26902426
Designing RNAs that form specific secondary structures is enabling better understanding and control of living systems through RNA-guided silencing, genome editing and protein organization. Little is known, however, about which...
3.
Treuille A, Das R
Trends Biochem Sci . 2014 Oct; 39(11):507-9. PMID: 25300714
Hypothesis-driven experimentation - the scientific method - can be subverted by fraud, irreproducibility, and lack of rigorous predictive tests. A robust solution to these problems may be the 'massive open...
4.
Lee J, Kladwang W, Lee M, Cantu D, Azizyan M, Kim H, et al.
Proc Natl Acad Sci U S A . 2014 Jan; 111(6):2122-7. PMID: 24469816
Self-assembling RNA molecules present compelling substrates for the rational interrogation and control of living systems. However, imperfect in silico models--even at the secondary structure level--hinder the design of new RNAs...
5.
Leaver-Fay A, Tyka M, Lewis S, Lange O, Thompson J, Jacak R, et al.
Methods Enzymol . 2010 Dec; 487:545-74. PMID: 21187238
We have recently completed a full re-architecturing of the ROSETTA molecular modeling program, generalizing and expanding its existing functionality. The new architecture enables the rapid prototyping of novel protocols by...
6.
Cooper S, Khatib F, Treuille A, Barbero J, Lee J, Beenen M, et al.
Nature . 2010 Aug; 466(7307):756-60. PMID: 20686574
People exert large amounts of problem-solving effort playing computer games. Simple image- and text-recognition tasks have been successfully 'crowd-sourced' through games, but it is not clear if more complex scientific...