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Adrian Smedowski

Explore the profile of Adrian Smedowski including associated specialties, affiliations and a list of published articles. Areas
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Articles 36
Citations 331
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Recent Articles
1.
Swierczynska M, Tronina A, Smedowski A
Redox Biol . 2025 Jan; 80:103495. PMID: 39813957
Myopia is an evolving global health challenge, with estimates suggesting that by 2050 it will affect half of the world's population, becoming the leading cause of irreversible vision loss. Moreover,...
2.
Bresciani G, Manai F, Felszeghy S, Smedowski A, Kaarniranta K, Amadio M
Pharmacol Res . 2024 Aug; 208:107380. PMID: 39216841
Age-related macular degeneration (AMD) is a common retinal pathology characterized by degeneration of macula's retinal pigment epithelium (RPE) and photoreceptors, visual impairment, or loss. Compared to wet AMD, dry AMD...
3.
Liu X, Pacwa A, Bresciani G, Swierczynska M, Dorecka M, Smedowski A
Mol Med . 2024 Jul; 30(1):109. PMID: 39060957
Primary cilia are sensory organelles that extend from the cellular membrane and are found in a wide range of cell types. Cilia possess a plethora of vital components that enable...
4.
Bugara K, Pacwa A, Smedowski A
Front Neurosci . 2024 Apr; 18:1363170. PMID: 38562304
Glaucoma is a complex and progressive disease that primarily affects the optic nerve axons, leading to irreversible vision loss. Although the exact molecular mechanisms underlying glaucoma pathogenesis are not fully...
5.
Wygledowska-Promienska D, Swierczynska M, Spiewak D, Pojda-Wilczek D, Tronina A, Dorecka M, et al.
Int J Mol Sci . 2024 Mar; 25(5). PMID: 38474172
Aland island eye disease (AIED), an incomplete form of X-linked congenital stationary night blindness (CSNB2A), and X-linked cone-rod dystrophy type 3 (CORDX3) display many overlapping clinical findings. They result from...
6.
Akhtar S, Smedowski A, Khan A, Debasi H, Mofty H, Samivel R, et al.
Exp Eye Res . 2024 Jan; 239:109780. PMID: 38176513
Corneal collagen cross-linking (CXL) is widely used to treat keratoconus and ecstatic corneal disorders. The present studies were carried out to investigate the distribution of glycosaminoglycans (GAGs) and collagen fibril...
7.
Hajduga-Szewczyk M, Smedowski A, Filipecka I, Mrukwa-Kominek E
Front Med (Lausanne) . 2023 Dec; 10:1273889. PMID: 38076245
Purpose: Micro-invasive glaucoma surgery involves a group of treatment methods associated with a low rate of side effects and good effectiveness outcomes. One of the most frequently performed procedures belonging...
8.
Manai F, Smedowski A, Kaarniranta K, Comincini S, Amadio M
J Control Release . 2023 Nov; 365:448-468. PMID: 38013069
Nanoscale extracellular vesicles (EVs), consisting of exomers, exosomes and microvesicles/ectosomes, have been extensively investigated in the last 20 years, although their biological role is still something of a mystery. EVs...
9.
Sulak R, Liu X, Smedowski A
Neural Regen Res . 2023 Jul; 19(1):92-99. PMID: 37488850
Gene therapies, despite of being a relatively new therapeutic approach, have a potential to become an important alternative to current treatment strategies in glaucoma. Since glaucoma is not considered a...
10.
Jamrozik D, Dutczak R, Machowicz J, Wojtyniak A, Smedowski A, Pietrucha-Dutczak M
Antioxidants (Basel) . 2023 Jun; 12(6). PMID: 37371981
Metallothioneins are the metal-rich proteins that play important roles in metal homeostasis and detoxification. Moreover, these proteins protect cells against oxidative stress, inhibit proapoptotic mechanisms and enhance cell differentiation and...