Adrian Nanez
Overview
Explore the profile of Adrian Nanez including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
424
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0
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Recent Articles
1.
Pettus L, Bourbeau M, Bradley J, Bartberger M, Chen K, Hickman D, et al.
J Med Chem
. 2019 Oct;
63(5):2263-2281.
PMID: 31589043
β-Site amyloid precursor protein cleaving enzyme 1 (BACE1) is an aspartyl protease that plays a key role in the production of amyloid β (Aβ) in the brain and has been...
2.
Ramos K, Stribinskis V, Steffen M, Nanez A, Montoya-Durango D, He Q
Oxid Med Cell Longev
. 2013 Mar;
2013:628615.
PMID: 23476722
This laboratory previously identified an albumin-like protein (denoted as p70) as a component of the macromolecular complex assembled within the 5'-regulatory region of redox-sensitive genes in vascular smooth muscle cells...
3.
Falahatpisheh M, Nanez A, Ramos K
Mol Med
. 2011 Aug;
17(11-12):1275-84.
PMID: 21863216
Mounting evidence suggests that the blueprint of chronic renal disease is established during early development by environmental cues that dictate alterations in differentiation programming. Here we show that aryl hydrocarbon...
4.
Nanez A, Ramos I, Ramos K
Environ Health Perspect
. 2011 Aug;
119(12):1745-53.
PMID: 21803694
Background: The use of experimental model systems has expedited the elucidation of pathogenetic mechanisms of renal developmental disease in humans and the identification of genes that orchestrate developmental programming during...
5.
Ramos K, Montoya-Durango D, Teneng I, Nanez A, Stribinskis V
Birth Defects Res A Clin Mol Teratol
. 2011 Mar;
91(8):693-702.
PMID: 21384534
Background: L1 retroelements may play a central role in morphogenesis through epigenetic mechanisms involving recruitment of chromatin modifying protein complexes. Retroelements are repressed in terminally differentiated cells, and highly active...
6.
Alexander A, Cai S, Kim J, Nanez A, Sahin M, Maclean K, et al.
Proc Natl Acad Sci U S A
. 2010 Feb;
107(9):4153-8.
PMID: 20160076
Ataxia-telangiectasia mutated (ATM) is a cellular damage sensor that coordinates the cell cycle with damage-response checkpoints and DNA repair to preserve genomic integrity. However, ATM also has been implicated in...
7.
Ramos K, Nanez A
Birth Defects Res C Embryo Today
. 2009 Jun;
87(2):192-7.
PMID: 19530133
Recent studies have identified AHR as a master regulator of Wilms' tumor suppressor gene (WT1) signaling in the developing kidney. Activation of AHR signaling by environmental chemical is associated with...
8.
Activation profiles of HSPA5 during the glomerular mesangial cell stress response to chemical injury
Falahatpisheh H, Nanez A, Montoya-Durango D, Qian Y, Tiffany-Castiglioni E, Ramos K
Cell Stress Chaperones
. 2007 Oct;
12(3):209-18.
PMID: 17915553
Environmental injury has been associated with endoplasmic reticulum (ER) stress, a response characterized by activation of the unfolded protein response, proteasomal degradation of proteins, and induction of HSPA5, also known...
9.
Ramos K, Steffen M, Falahatpisheh M, Nanez A
Environ Mol Mutagen
. 2007 Jun;
48(5):395-9.
PMID: 17567845
As the postgenomic era continues to unfold, a new wave of scientific investigation is upon us focusing on the application of genomic technologies to study the meanings encrypted on the...
10.
Bozulic L, Malik M, Powell D, Nanez A, Link A, Ramos K, et al.
Thromb Haemost
. 2007 Mar;
97(4):587-97.
PMID: 17393022
The plasma membrane Ca(2+)-ATPase (PMCA) plays an essential role in maintaining low cytosolic Ca(2+) in resting platelets. Earlier studies demonstrated that the 4b isoform of PMCA interacts via its C-terminal...