Adrian Cardenas
Overview
Explore the profile of Adrian Cardenas including associated specialties, affiliations and a list of published articles.
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11
Citations
306
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Recent Articles
1.
Singh A, Del-Valle-Anton L, de Juan Romero C, Zhang Z, Ortuno E, Mahesh A, et al.
Sci Adv
. 2024 Jun;
10(23):eadn1640.
PMID: 38838158
Folding of the cerebral cortex is a key aspect of mammalian brain development and evolution, and defects are linked to severe neurological disorders. Primary folding occurs in highly stereotyped patterns...
2.
Del-Valle-Anton L, Amin S, Cimino D, Neuhaus F, Dvoretskova E, Fernandez V, et al.
Sci Adv
. 2024 Mar;
10(13):eadn9998.
PMID: 38536915
Cortical neurogenesis follows a simple lineage: apical radial glia cells (RGCs) generate basal progenitors, and these produce neurons. How this occurs in species with expanded germinal zones and a folded...
3.
Vilchez-Acosta A, Manso Y, Cardenas A, Elias-Tersa A, Martinez-Losa M, Pascual M, et al.
Proc Natl Acad Sci U S A
. 2022 Sep;
119(37):e2120079119.
PMID: 36067316
The extracellular protein Reelin, expressed by Cajal-Retzius (CR) cells at early stages of cortical development and at late stages by GABAergic interneurons, regulates radial migration and the "inside-out" pattern of...
4.
Chinnappa K, Cardenas A, Prieto-Colomina A, Villalba A, Marquez-Galera A, Soler R, et al.
Sci Adv
. 2022 Jan;
8(2):eabj4010.
PMID: 35020425
The evolutionary expansion and folding of the mammalian cerebral cortex resulted from amplification of progenitor cells during embryonic development. This process was reversed in the rodent lineage after splitting from...
5.
Cardenas A, Borrell V
STAR Protoc
. 2021 Aug;
2(3):100692.
PMID: 34382018
electroporation has become a key technique to study genetic mechanisms of brain development. However, electroporation of the embryonic pallium in oviparous species, interesting for evolutionary studies but distinct from electroporation,...
6.
Repression of Irs2 by let-7 miRNAs is essential for homeostasis of the telencephalic neuroepithelium
Fernandez V, Martinez-Martinez M, Prieto-Colomina A, Cardenas A, Soler R, Dori M, et al.
EMBO J
. 2020 Sep;
39(21):e105479.
PMID: 32985705
Structural integrity and cellular homeostasis of the embryonic stem cell niche are critical for normal tissue development. In the telencephalic neuroepithelium, this is controlled in part by cell adhesion molecules...
7.
Cardenas A, Borrell V
Cell Mol Life Sci
. 2019 Sep;
77(8):1435-1460.
PMID: 31563997
The cerebral cortex varies dramatically in size and complexity between amniotes due to differences in neuron number and composition. These differences emerge during embryonic development as a result of variations...
8.
Cardenas A, Villalba A, de Juan Romero C, Pico E, Kyrousi C, Tzika A, et al.
Cell
. 2018 Jul;
174(3):590-606.e21.
PMID: 29961574
Cerebral cortex size differs dramatically between reptiles, birds, and mammals, owing to developmental differences in neuron production. In mammals, signaling pathways regulating neurogenesis have been identified, but genetic differences behind...
9.
Reillo I, de Juan Romero C, Cardenas A, Clasca F, Martinez-Martinez M, Borrell V
Cereb Cortex
. 2017 Sep;
27(9):4586-4606.
PMID: 28922855
Development of the cerebral cortex depends critically on the regulation of progenitor cell proliferation and fate. Cortical progenitor cells are remarkably diverse with regard to their morphology as well as...
10.
Martinez-Martinez M, de Juan Romero C, Fernandez V, Cardenas A, Gotz M, Borrell V
Nat Commun
. 2016 Jun;
7:11812.
PMID: 27264089
The outer subventricular zone (OSVZ) is a germinal layer playing key roles in the development of the neocortex, with particular relevance in gyrencephalic species such as human and ferret, where...