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Adrian Ally

Explore the profile of Adrian Ally including associated specialties, affiliations and a list of published articles. Areas
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Articles 14
Citations 6043
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Recent Articles
1.
Jones S, Taylor G, Chan S, Warren R, Hammond S, Bilobram S, et al.
Genes (Basel) . 2017 Dec; 8(12). PMID: 29232881
The beluga whale is a cetacean that inhabits arctic and subarctic regions, and is the only living member of the genus . The genome of the beluga whale was determined...
2.
Jones S, Haulena M, Taylor G, Chan S, Bilobram S, Warren R, et al.
Genes (Basel) . 2017 Dec; 8(12). PMID: 29232880
The northern sea otter inhabits coastal waters of the northern Pacific Ocean and is the largest member of the Mustelidae family. DNA sequencing methods that utilize microfluidic partitioned and non-partitioned...
3.
Morrissy A, Cavalli F, Remke M, Ramaswamy V, Shih D, Holgado B, et al.
Nat Genet . 2017 Apr; 49(5):780-788. PMID: 28394352
Spatial heterogeneity of transcriptional and genetic markers between physically isolated biopsies of a single tumor poses major barriers to the identification of biomarkers and the development of targeted therapies that...
4.
Morrissy A, Garzia L, Shih D, Zuyderduyn S, Huang X, Skowron P, et al.
Nature . 2016 Jan; 529(7586):351-7. PMID: 26760213
The development of targeted anti-cancer therapies through the study of cancer genomes is intended to increase survival rates and decrease treatment-related toxicity. We treated a transposon-driven, functional genomic mouse model...
5.
Linehan W, Spellman P, Ricketts C, Creighton C, Fei S, Davis C, et al.
N Engl J Med . 2015 Nov; 374(2):135-45. PMID: 26536169
Background: Papillary renal-cell carcinoma, which accounts for 15 to 20% of renal-cell carcinomas, is a heterogeneous disease that consists of various types of renal cancer, including tumors with indolent, multifocal...
6.
Brat D, Verhaak R, Aldape K, Yung W, Salama S, Cooper L, et al.
N Engl J Med . 2015 Jun; 372(26):2481-98. PMID: 26061751
Background: Diffuse low-grade and intermediate-grade gliomas (which together make up the lower-grade gliomas, World Health Organization grades II and III) have highly variable clinical behavior that is not adequately predicted...
7.
Ley T, Miller C, Ding L, Raphael B, Mungall A, Robertson A, et al.
N Engl J Med . 2013 May; 368(22):2059-74. PMID: 23634996
Background: Many mutations that contribute to the pathogenesis of acute myeloid leukemia (AML) are undefined. The relationships between patterns of mutations and epigenetic phenotypes are not yet clear. Methods: We...
8.
Pugh T, Morozova O, Attiyeh E, Asgharzadeh S, Wei J, Auclair D, et al.
Nat Genet . 2013 Jan; 45(3):279-84. PMID: 23334666
Neuroblastoma is a malignancy of the developing sympathetic nervous system that often presents with widespread metastatic disease, resulting in survival rates of less than 50%. To determine the spectrum of...
9.
Griffith M, Griffith O, Mwenifumbo J, Goya R, Morrissy A, Morin R, et al.
Nat Methods . 2010 Sep; 7(10):843-7. PMID: 20835245
In alternative expression analysis by sequencing (ALEXA-seq), we developed a method to analyze massively parallel RNA sequence data to catalog transcripts and assess differential and alternative expression of known and...
10.
Griffith M, Tang M, Griffith O, Morin R, Chan S, Asano J, et al.
Nat Methods . 2008 Feb; 5(2):118. PMID: 18235430
No abstract available.