Adnane Achour
Overview
Explore the profile of Adnane Achour including associated specialties, affiliations and a list of published articles.
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Articles
111
Citations
2038
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Recent Articles
1.
Bilev E, Wild N, Momayyezi P, Sala B, Sun R, Sandalova T, et al.
PLoS Pathog
. 2024 Dec;
20(12):e1012755.
PMID: 39652590
In addition to adaptive immunity, natural killer (NK) cells of the innate immune system contribute to the control of viral infections. The HLA-E-restricted SARS-CoV-2 Nsp13232-240 epitope VMPLSAPTL renders infected cells...
2.
SARS-CoV-2 N protein recruits G3BP to double membrane vesicles to promote translation of viral mRNAs
Long S, Guzyk M, Perez Vidakovics L, Han X, Sun R, Wang M, et al.
Nat Commun
. 2024 Dec;
15(1):10607.
PMID: 39638802
Ras-GTPase-activating protein SH3-domain-binding proteins (G3BP) are critical for the formation of stress granules (SGs) through their RNA- and ribosome-binding properties. SARS-CoV-2 nucleocapsid (N) protein exhibits strong binding affinity for G3BP...
3.
Wallerstein J, Han X, Levkovets M, Lesovoy D, Malmodin D, Mirabello C, et al.
Commun Biol
. 2024 Jul;
7(1):868.
PMID: 39014105
Mucosa-associated lymphoid tissue lymphoma-translocation protein 1 (MALT1) is an attractive target for the development of modulatory compounds in the treatment of lymphoma and other cancers. While the three-dimensional structure of...
4.
Tittarelli A, Pereda C, Gleisner M, Lopez M, Flores I, Tempio F, et al.
Vaccines (Basel)
. 2024 Apr;
12(4).
PMID: 38675738
Cancer vaccines present a promising avenue for treating immune checkpoint blockers (ICBs)-refractory patients, fostering immune responses to modulate the tumor microenvironment. We revisit a phase I/II trial using Tumor Antigen-Presenting...
5.
Middelburg J, Ghaffari S, Schoufour T, Sluijter M, Schaap G, Goynuk B, et al.
Cell Rep
. 2023 Dec;
42(12):113516.
PMID: 38048225
The immune checkpoint NKG2A/CD94 is a promising target for cancer immunotherapy, and its ligand major histocompatibility complex E (MHC-E) is frequently upregulated in cancer. NKG2A/CD94-mediated inhibition of lymphocytes depends on...
6.
Agback T, Lesovoy D, Han X, Lomzov A, Sun R, Sandalova T, et al.
Commun Biol
. 2023 Nov;
6(1):1193.
PMID: 38001280
The dengue protease NS2B/NS3pro has been reported to adopt either an 'open' or a 'closed' conformation. We have developed a conformational filter that combines NMR with MD simulations to identify...
7.
Liao X, Ozcan M, Shi M, Kim W, Jin H, Li X, et al.
Bioinformatics
. 2023 Nov;
39(11).
PMID: 37930015
Motivation: Many approaches in systems biology have been applied in drug repositioning due to the increased availability of the omics data and computational biology tools. Using a multi-omics integrated network,...
8.
Almazan N, Sala B, Sandalova T, Sun Y, Resink T, Cichocki F, et al.
Front Immunol
. 2023 Oct;
14:1230718.
PMID: 37809084
Introduction: Human cytomegalovirus (HCMV) reactivation causes complications in immunocompromised patients after hematopoietic stem cell transplantation (HSCT), significantly increasing morbidity and mortality. Adaptive Natural Killer (aNK) cells undergo a persistent reconfiguration...
9.
Schulte T, Panas M, Han X, Williams L, Kedersha N, Fleck J, et al.
Open Biol
. 2023 May;
13(5):220369.
PMID: 37161291
G3BP is the central node within stress-induced protein-RNA interaction networks known as stress granules (SGs). The SG-associated proteins Caprin-1 and USP10 bind mutually exclusively to the NTF2 domain of G3BP1,...
10.
Qiu T, Jahangiri A, Han X, Lesovoy D, Agback T, Agback P, et al.
Chem Commun (Camb)
. 2023 Apr;
59(36):5475-5478.
PMID: 37070867
Nuclear magnetic resonance (NMR) spectroscopy has become a formidable tool for biochemistry and medicine. Although -coupling carries essential structural information it may also limit the spectral resolution. Homonuclear decoupling remains...