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Adewonuola Alase

Explore the profile of Adewonuola Alase including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 253
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Recent Articles
1.
Carter L, Md Yusof M, Wigston Z, Plant D, Wenlock S, Alase A, et al.
Ann Rheum Dis . 2024 May; 83(10):1322-1334. PMID: 38740438
Objective: Mechanisms underpinning clinical evolution to systemic lupus erythematosus (SLE) from preceding antinuclear antibodies (ANA) positivity are poorly understood. This study aimed to understand blood immune cell transcriptional signatures associated...
2.
Carter L, Alase A, Wigston Z, Psarras A, Burska A, Sutton E, et al.
Arthritis Rheumatol . 2022 Nov; 75(5):697-710. PMID: 36409591
Objective: Gene expression profiles are associated with the clinical heterogeneity of systemic lupus erythematosus (SLE) but are not well studied as biomarkers for therapy. We studied gene expression and response...
3.
Psarras A, Antanaviciute A, Alase A, Carr I, Wittmann M, Emery P, et al.
J Immunol . 2021 Jan; 206(4):785-796. PMID: 33441439
Human plasmacytoid dendritic cells (pDCs) play a vital role in modulating immune responses. They can produce massive amounts of type I IFNs in response to nucleic acids via TLRs, but...
4.
Psarras A, Alase A, Antanaviciute A, Carr I, Md Yusof M, Wittmann M, et al.
Nat Commun . 2020 Dec; 11(1):6149. PMID: 33262343
Autoimmune connective tissue diseases arise in a stepwise fashion from asymptomatic preclinical autoimmunity. Type I interferons have a crucial role in the progression to established autoimmune diseases. The cellular source...
5.
Bridgewood C, Alase A, Watad A, Wittmann M, Cuthbert R, McGonagle D
Inflamm Res . 2019 May; 68(6):427. PMID: 31065724
The original article can be found online.
6.
Bridgewood C, Alase A, Watad A, Wittmann M, Cuthbert R, McGonagle D
Inflamm Res . 2019 Apr; 68(6):423-426. PMID: 30989239
Objective: The heterodimeric IL-12 family member cytokines including, IL-12, IL-23, IL-27, and IL-35 and have multiple roles in regulating innate and adaptive immunity with crucial functions in inflammatory disorders such...
7.
Md Yusof M, Psarras A, El-Sherbiny Y, Hensor E, Dutton K, Ul-Hassan S, et al.
Ann Rheum Dis . 2018 Jun; 77(10):1432-1439. PMID: 29929956
Objective: To evaluate clinical, interferon and imaging predictors of progression from 'At Risk' to autoimmune connective tissue diseases (AI-CTDs). Methods: A prospective observational study was conducted in At-Risk of AI-CTD...
8.
Berekmeri A, Latzko A, Alase A, Macleod T, Ainscough J, Laws P, et al.
J Allergy Clin Immunol . 2018 May; 142(3):988-991.e4. PMID: 29782895
No abstract available.
9.
Bridgewood C, Stacey M, Alase A, Lagos D, Graham A, Wittmann M
Exp Dermatol . 2016 Sep; 26(5):402-408. PMID: 27673278
Interleukin-36 cytokines are predominantly expressed by epithelial cells. Significant upregulation of epidermal IL-36 is now a recognised characteristic of psoriatic skin inflammation. IL-36 is known to induce inflammatory responses in...
10.
Macleod T, Doble R, McGonagle D, Wasson C, Alase A, Stacey M, et al.
Sci Rep . 2016 Apr; 6:24880. PMID: 27101808
The interleukin-36 receptor antagonist (IL-36Ra) which regulates IL-36α, -β and -γ is linked to psoriatic inflammation, especially loss-of-function mutations in pustular psoriasis subtypes. As observed with other IL-1 superfamily proteins,...