Adeline Guais
Overview
Explore the profile of Adeline Guais including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
356
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Recent Articles
1.
Schwartz L, Guais A, Israel M, Junod B, Steyaert J, Crespi E, et al.
Invest New Drugs
. 2012 Jul;
31(2):256-64.
PMID: 22797854
Cellular metabolic alterations are now well described as implicated in cancer and some strategies are currently developed to target these different pathways. In previous papers, we demonstrated that a combination...
2.
Baronzio G, Schwartz L, Kiselevsky M, Guais A, Sanders E, Milanesi G, et al.
Anticancer Res
. 2012 Jan;
32(2):405-14.
PMID: 22287726
Tumor interstitial fluid (TIF) is a watery phase that accumulates inside the tumor interstitium. Its genesis and fate depend on various factors, namely tumor type, metabolic state of the tumor,...
3.
Guais A, Brand G, Jacquot L, Karrer M, Dukan S, Grevillot G, et al.
Chem Res Toxicol
. 2011 Jul;
24(12):2061-70.
PMID: 21732636
The toxicity of carbon dioxide has been established for close to a century. A number of animal experiments have explored both acute and long-term toxicity with respect to the lungs,...
4.
Abolhassani M, Guais A, Sanders E, Campion F, Fichtner I, Bonte J, et al.
Invest New Drugs
. 2011 Jun;
30(4):1331-42.
PMID: 21655919
Alterations in metabolic pathways are known to characterize cancer. In order to suppress cancer growth, however, multiple proteins involved in these pathways have to be targeted simultaneously. We have developed...
5.
Guais A, Baronzio G, Sanders E, Campion F, Mainini C, Fiorentini G, et al.
Invest New Drugs
. 2010 Oct;
30(1):200-11.
PMID: 20931262
Altered metabolism of cancer first highlighted by Otto Warburg has a long history. Although ignored for a considerable amount of time, it is now receiving substantial attention. We recently published...
6.
Schwartz L, Guais A, Chaumet-Riffaud P, Grevillot G, Sasco A, Molina T, et al.
Inhal Toxicol
. 2010 Apr;
22(7):543-51.
PMID: 20387988
Tobacco smoking is responsible for a vast array of diseases, particularly chronic bronchitis and lung cancer. It is still unclear which constituent(s) of the smoke is responsible for its toxicity....
7.
Schwartz L, Abolhassani M, Guais A, Sanders E, Steyaert J, Campion F, et al.
Oncol Rep
. 2010 Apr;
23(5):1407-16.
PMID: 20372858
The impact of metabolic dysregulation on tumor development has long been established. We have targeted two enzymes that are altered during carcinogenesis: pyruvate dehydrogenase (PDH), which is down-regulated, and ATP...
8.
Schwartz L, Guais A, Pooya M, Abolhassani M
J Inflamm (Lond)
. 2009 Jun;
6:21.
PMID: 19549308
Background: There are several reports suggesting that hyperosmolarity induces inflammation. We recently showed that Dextran Sodium Sulfate causes inflammatory bowel disease due to hyperosmolarity. The aim of this study was...
9.
Abolhassani M, Guais A, Chaumet-Riffaud P, Sasco A, Schwartz L
Am J Physiol Lung Cell Mol Physiol
. 2009 Jan;
296(4):L657-65.
PMID: 19136578
The aim of this study was to assess whether one of the most common poisons of cellular respiration, i.e., carbon dioxide, is proinflammatory. CO(2) is naturally present in the atmosphere...
10.
Guillemin C, Maleszewska M, Guais A, Maes J, Rouyez M, Yacia A, et al.
Stem Cells
. 2008 Nov;
27(1):108-15.
PMID: 18974210
To further clarify the contribution of nuclear architecture in the regulation of gene expression patterns during differentiation of human multipotent cells, we analyzed expression status, histone modifications, and subnuclear positioning...