Adele Chimento
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Explore the profile of Adele Chimento including associated specialties, affiliations and a list of published articles.
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Recent Articles
11.
Chimento A, De Luca A, Nocito M, Avena P, Padula D, Zavaglia L, et al.
Cells
. 2020 Sep;
9(9).
PMID: 32957524
Estrogen signaling plays important roles in testicular functions and tumorigenesis. Fifteen years ago, it was discovered that a member of the G protein-coupled receptor family, GPR30, which binds also with...
12.
Trotta F, Avena P, Chimento A, Rago V, De Luca A, Sculco S, et al.
Mol Cancer Ther
. 2020 Jun;
19(9):1909-1921.
PMID: 32546662
Mitotane causes hypercholesterolemia in patients with adrenocortical carcinoma (ACC). We suppose that cholesterol increases within the tumor and can be used to activate proliferative pathways. In this study, we used...
13.
Essafi Rhouma H, Trabelsi N, Chimento A, Benincasa C, Tamaalli A, Perri E, et al.
Nat Prod Res
. 2019 Jul;
35(11):1836-1839.
PMID: 31282742
The aim of this study was to characterise phenolic compounds of olive flower obtained from Olive tree cultivar and to investigate their anticancer effect on MCF-7 cells. Phenolic characterisation was...
14.
Chimento A, De Amicis F, Sirianni R, Sinicropi M, Puoci F, Casaburi I, et al.
Int J Mol Sci
. 2019 Mar;
20(6).
PMID: 30893846
Resveratrol (3,5,4'-trihydroxystilbene; RSV) is a natural nonflavonoid polyphenol present in many species of plants, particularly in grapes, blueberries, and peanuts. Several in vitro and in vivo studies have shown that...
15.
De Amicis F, Chimento A, Montalto F, Casaburi I, Sirianni R, Pezzi V
Int J Mol Sci
. 2019 Mar;
20(5).
PMID: 30832393
Extensive research over the past 25 years in hormone-dependent cancers, such as breast cancer and prostate cancer, has identified the molecular mechanisms driven by steroid receptors, elucidating the interplay between...
16.
Chimento A, Casaburi I, Avena P, Trotta F, De Luca A, Rago V, et al.
Front Endocrinol (Lausanne)
. 2019 Feb;
9:807.
PMID: 30719023
Cholesterol is essential for cell function and viability. It is a component of the plasma membrane and lipid rafts and is a precursor for bile acids, steroid hormones, and Vitamin...
17.
Mancuso R, Ziccarelli I, Chimento A, Marino N, Ca N, Sirianni R, et al.
iScience
. 2018 Nov;
3:279-288.
PMID: 30428327
The development of efficient synthetic strategies for the discovery of novel antitumor molecules is a major goal in current research. In this context, we report here a catalytic double cyclization...
18.
Casaburi I, Chimento A, De Luca A, Nocito M, Sculco S, Avena P, et al.
Front Endocrinol (Lausanne)
. 2018 Sep;
9:525.
PMID: 30254608
The estrogen-related receptors (ERRs) are important members of nuclear receptors which contain three isoforms (α, β, and γ). ERRα is the best-characterized isoform expressed mainly in high-energy demanding tissues where...
19.
Casaburi I, Avena P, De Luca A, Sirianni R, Rago V, Chimento A, et al.
Oncotarget
. 2018 Feb;
8(70):115609-115619.
PMID: 29383185
We previously demonstrated that treatment of the H295R adrenocortical cancer cell line with the non-steroidal, high-affinity GPER (G protein-coupled estrogen receptor 1) agonist G-1 reduced tumor growth and through a...
20.
De Luca A, Avena P, Sirianni R, Chimento A, Fallo F, Pilon C, et al.
Cells
. 2017 Nov;
6(4).
PMID: 29112114
PELP1 acts as an estrogen receptor (ER) coactivator that exerts an essential role in the ER's functions. ER coregulators have a critical role in the progression and response to hormonal...