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Adela Navarro

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Articles 18
Citations 136
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Recent Articles
1.
Goni-Oloriz M, Garaikoetxea Zubillaga M, San Ildefonso-Garcia S, Fernandez-Celis A, Castillo P, Navarro A, et al.
Am J Physiol Heart Circ Physiol . 2025 Jan; 328(3):H639-H647. PMID: 39832303
Diabetes mellitus (DM) increases the risk of aortic stenosis (AS) and worsens its pathophysiology in a sex-specific manner. Aldosterone/mineralocorticoid receptor (Aldo/MR) pathway participates in the early stages of AS and...
2.
Tiraplegui C, Garaikoetxea M, Garaikoetxea Zubillaga M, Sadaba A, San Ildefonso-Garcia S, Goni-Oloriz M, et al.
Am J Physiol Heart Circ Physiol . 2025 Jan; 328(3):H693-H710. PMID: 39804841
Aortic regurgitation (AR) is more prevalent in males, although cellular and molecular mechanisms underlying the sex differences in prevalence and pathophysiology are unknown. This study evaluates the impact of sex...
3.
Boiko O, Garcia-Alonso I, Navarro A, Maldonado A, Prieto S, Llorente A, et al.
Prog Transplant . 2024 Oct; 34(4):199-203. PMID: 39396542
Introduction: Lymphocele is a common complication post-kidney transplantation, influenced by various factors including surgical technique, graft vessel count, operator experience, body mass index, ischemia time, and immunotherapy regimens. Project Aims:...
4.
Vera A, Lanaspa A, Jimenez O, Navarro A, Basurte M, Beunza M, et al.
Catheter Cardiovasc Interv . 2024 Oct; 104(6):1196-1203. PMID: 39350481
Background: Coronary embolism (CE) is an uncommon cause of non-atherosclerotic acute myocardial infarction (AMI). Although atrial fibrillation (AF) is the main cause of CE, evidence of clinical, biochemical, echocardiographic, angiographic...
5.
Matilla L, Martin-Nunez E, Navarro A, Garaikoetxea M, Fernandez-Celis A, Goni-Oloriz M, et al.
Biochem Pharmacol . 2024 Jun; 226:116336. PMID: 38844264
The pathological mechanisms underlying the sex-dependent presentation of calcific aortic stenosis (AS) remain poorly understood. We aim to analyse sex-specific responses of valve interstitial cells (VICs) to calcific environments and...
6.
Jover E, Martin-Nunez E, Garaikoetxea M, Matilla L, Blanco-Colio L, Perez-Saez J, et al.
FASEB J . 2024 Feb; 38(3):e23447. PMID: 38329326
We aimed to analyze sex-related differences in galectin-1 (Gal-1), a β-galactoside-binding lectin, in aortic stenosis (AS) and its association with the inflammatory and fibrocalcific progression of AS. Gal-1 was determined...
7.
Matilla L, Martin-Nunez E, Garaikoetxea M, Navarro A, Tamayo I, Fernandez-Celis A, et al.
Biol Sex Differ . 2023 Oct; 14(1):72. PMID: 37875993
Background: Aortic stenosis (AS) is characterized by inflammation, fibrosis, osteogenesis and angiogenesis. Men and women develop these mechanisms differently. Galectin-3 (Gal-3) is a pro-inflammatory and pro-osteogenic lectin in AS. In...
8.
Martin-Nunez E, Goni-Oloriz M, Matilla L, Garaikoetxea M, Mourino-Alvarez L, Navarro A, et al.
Cardiovasc Diabetol . 2023 Oct; 22(1):280. PMID: 37848892
Background: Diabetes mellitus (DM) accelerates the progression of aortic stenosis (AS), but how their underlying molecular mechanisms interact is not clear. Moreover, whether DM contributes to clinically relevant sex-differences in...
9.
Arrieta V, Jover E, Navarro A, Martin-Nunez E, Garaikoetxea M, Matilla L, et al.
Rev Esp Cardiol (Engl Ed) . 2022 Dec; 76(9):679-689. PMID: 36565751
Introduction And Objectives: Patients with aortic stenosis (AS) exhibit left ventricular (LV) remodeling and replacement myocardial fibrosis (RMF). Whether sST2 is associated with RMF measured by cardiac magnetic resonance and...
10.
Jover E, Matilla L, Martin-Nunez E, Garaikoetxea M, Navarro A, Fernandez-Celis A, et al.
Biol Sex Differ . 2022 Dec; 13(1):71. PMID: 36510294
Background: Accumulating evidence suggest the existence of sex-related differences in the pathogenesis of aortic stenosis (AS) with inflammation, oxidative stress, fibrosis and calcification being over-represented in men. Neutrophil gelatinase-associated lipocalin...