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Adedeji K Adebayo

Explore the profile of Adedeji K Adebayo including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 95
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Recent Articles
1.
Bhat-Nakshatri P, Gao H, Khatpe A, Adebayo A, McGuire P, Erdogan C, et al.
Nat Med . 2024 Aug; 30(12):3482-3494. PMID: 39122969
Single-nucleus analysis allows robust cell-type classification and helps to establish relationships between chromatin accessibility and cell-type-specific gene expression. Here, using samples from 92 women of several genetic ancestries, we developed...
2.
Adebayo A, Bhat-Nakshatri P, Davis C, Angus S, Erdogan C, Gao H, et al.
iScience . 2024 Jun; 27(6):110068. PMID: 38872973
Most cells in solid tumors are exposed to oxygen levels between 0.5% and 5%. We developed an approach that allows collection, processing, and evaluation of cancer and non-cancer cells under...
3.
Wang R, Khatpe A, Kumar B, Mang H, Batic K, Adebayo A, et al.
Cancer Res Commun . 2024 Apr; 4(5):1282-1295. PMID: 38651826
Significance: Mutant RAS- and PIK3CA-driven breast cancers distinctly affect the function of skeletal muscle. Therefore, research and therapeutic targeting of cancer-induced systemic effects need to take aberrant cancer genome into...
4.
Adebayo A, Nakshatri H
Cancer Res . 2022 Sep; 82(23):4313-4321. PMID: 36169928
Oxygen (O2) plays a key role in cellular homeostasis. O2 levels are tightly regulated in vivo such that each tissue receives an optimal amount to maintain physiologic status. Physiologic O2...
5.
Kumar B, Adebayo A, Prasad M, Capitano M, Wang R, Bhat-Nakshatri P, et al.
Sci Adv . 2022 Jan; 8(2):eabh3375. PMID: 35020422
Preclinical studies of primary cancer cells are typically done after tumors are removed from patients or animals at ambient atmospheric oxygen (O, ~21%). However, O concentrations in organs are in...
6.
Khatpe A, Adebayo A, Herodotou C, Kumar B, Nakshatri H
Cancers (Basel) . 2021 Jan; 13(3). PMID: 33498407
Signaling from estrogen receptor alpha (ERα) and its ligand estradiol (E2) is critical for growth of ≈70% of breast cancers. Therefore, several drugs that inhibit ERα functions have been in...
7.
Oyagbemi A, Adebiyi O, Adigun K, Ogunpolu B, Falayi O, Hassan F, et al.
Environ Toxicol . 2019 Nov; 35(2):242-253. PMID: 31710167
Fluoride is an environmental contaminant that is ubiquitously present in air, water, and soil. It is commonly added in minute quantity to drinking water, toothpaste, and mouth rinses to prevent...
8.
Adebayo A, Adebiyi A, Oladapo O, Ogah O, Aje A, Ojji D, et al.
BMC Cardiovasc Disord . 2009 Nov; 9:52. PMID: 19922629
Background: The study aimed to determine the frequency and characteristics of heart failure with normal EF in a native African population with heart failure. Methods: It was a hospital cohort...
9.
Salako B, Ogah O, Adebiyi A, Oladapo O, Aje A, Adebayo A, et al.
Ann Afr Med . 2009 Nov; 8(3):156-62. PMID: 19884691
Background: Hypertension is a disease characterized by end-organ complications, leading to high morbidity and mortality in many cases. People with untreated or uncontrolled hypertension often run the risk of developing...
10.
Ojji D, Adebiyi A, Oladapo O, Adeleye J, Aje A, Ogah O, et al.
Prev Cardiol . 2009 Sep; 12(4):184-8. PMID: 19751482
Left ventricular hypertrophy has been linked with diabetes mellitus and abnormal glucose tolerance in several studies. Most previous studies have been carried out in the western world with dearth of...