Adam R Hersperger
Overview
Explore the profile of Adam R Hersperger including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
748
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0
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Recent Articles
1.
Morgis R, Haan K, Schrey J, Zimmerman R, Hersperger A
Virology
. 2021 Sep;
564:1-12.
PMID: 34560573
Many poxviruses produce proteins that are related to epidermal growth factor (EGF). Prior genome sequencing of ectromelia virus revealed a gene predicted to produce a protein with homology to EGF,...
2.
Forsyth K, Roy N, Peauroi E, DeHaven B, Wold E, Hersperger A, et al.
PLoS Pathog
. 2020 Aug;
16(8):e1008685.
PMID: 32745153
Smallpox and monkeypox pose severe threats to human health. Other orthopoxviruses are comparably virulent in their natural hosts, including ectromelia, the cause of mousepox. Disease severity is linked to an...
3.
Magee M, Abraham T, Baybutt T, Flickinger Jr J, Ridge N, Marszalowicz G, et al.
Cancer Immunol Res
. 2018 Apr;
6(5):509-516.
PMID: 29615399
One major hurdle to the success of adoptive T-cell therapy is the identification of antigens that permit effective targeting of tumors in the absence of toxicities to essential organs. Previous...
4.
Frey T, Forsyth K, Sheehan M, De Haven B, Pevarnik J, Hand E, et al.
Virology
. 2018 Mar;
518:335-348.
PMID: 29602068
All known orthopoxviruses, including ectromelia virus (ECTV), contain a gene in the E3L family. The protein product of this gene, E3, is a double-stranded RNA-binding protein. It can impact host...
5.
Frey T, Lehmann M, Ryan C, Pizzorno M, Sutter G, Hersperger A
Virology
. 2017 Jun;
509:98-111.
PMID: 28628829
Most orthopoxviruses, including vaccinia virus (VACV), contain genes in the E3L and K3L families. The protein products of these genes have been shown to combat PKR, a host defense pathway....
6.
Hand E, Haller S, Peng C, Rothenburg S, Hersperger A
PLoS One
. 2015 Mar;
10(3):e0119189.
PMID: 25734776
As a group, poxviruses have been shown to infect a wide variety of animal species. However, there is individual variability in the range of species able to be productively infected....
7.
Siciliano N, Hersperger A, Lacuanan A, Xu R, Sidney J, Sette A, et al.
J Virol
. 2014 Jun;
88(17):10078-91.
PMID: 24965457
Unlabelled: The factors that determine CD4+ T cell (TCD4+) specificities, functional capacity, and memory persistence in response to complex pathogens remain unclear. We explored these parameters in the C57BL/6 mouse...
8.
Hersperger A, Siciliano N, DeHaven B, Snook A, Eisenlohr L
J Virol
. 2014 Jun;
88(16):9472-5.
PMID: 24899206
We assessed several routes of immunization with vaccinia virus (VACV) in protecting mice against ectromelia virus (ECTV). By a wide margin, skin scarification provided the greatest protection. Humoral immunity and...
9.
Fang M, Siciliano N, Hersperger A, Roscoe F, Hu A, Ma X, et al.
Proc Natl Acad Sci U S A
. 2012 Jun;
109(25):9983-8.
PMID: 22665800
CD4(+) T cells are generally regarded as helpers and regulators of the immune response. Although cytolytic CD4(+) T cells have been described, whether those generated during the course of a...
10.
Hersperger A, Siciliano N, Eisenlohr L
J Virol
. 2012 Apr;
86(13):7298-309.
PMID: 22532670
Vaccinia virus (VACV) stimulates long-term immunity against highly pathogenic orthopoxvirus infection of humans (smallpox) and mice (mousepox [ectromelia virus {ECTV}]) despite the lack of a natural host-pathogen relationship with either...