Adam P Geballe
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Explore the profile of Adam P Geballe including associated specialties, affiliations and a list of published articles.
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49
Citations
1650
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Recent Articles
1.
Alwine J, Goodrum F, Banfield B, Bloom D, Britt W, Broadbent A, et al.
J Virol
. 2024 Aug;
98(9):e0124024.
PMID: 39087765
Science is humanity's best insurance against threats from nature, but it is a fragile enterprise that must be nourished and protected. The preponderance of scientific evidence indicates a natural origin...
2.
Kelnhofer-Millevolte L, Smith J, Nguyen D, Wilson L, Lewis H, Arnold E, et al.
bioRxiv
. 2024 Jun;
PMID: 38915666
Viral invasion of the host cell causes some of the most dramatic changes in biology. Human cytomegalovirus (HCMV) extensively remodels host cells, altering nuclear shape and generating a cytoplasmic viral-induced...
3.
Bayer A, Child S, Malik H, Geballe A
J Virol
. 2023 Oct;
97(10):e0083023.
PMID: 37796130
Herpesviruses present a major global disease burden. Understanding the host cell mechanisms that block viral infections, as well as how viruses can evolve to counteract these host defenses, is critically...
4.
Olson A, Kang Y, Ladha A, Zhu S, Lim C, Nabet B, et al.
PLoS Pathog
. 2023 Sep;
19(9):e1011169.
PMID: 37669313
Kaposi's sarcoma-associated herpesvirus (KSHV) causes several human diseases including Kaposi's sarcoma (KS), a leading cause of cancer in Africa and in patients with AIDS. KS tumor cells harbor KSHV predominantly...
5.
Bayer A, Child S, Malik H, Geballe A
bioRxiv
. 2023 Jul;
PMID: 37398298
Importance: Herpesviruses present a major global disease burden. Understanding the host cell mechanisms that block viral infections as well as how viruses can evolve to counteract these host defenses is...
6.
Olson A, Kang Y, Ladha A, Lim C, Lagunoff M, Gujral T, et al.
bioRxiv
. 2023 Feb;
PMID: 36778430
Author Summary: Kaposi's sarcoma-associated herpesvirus (KSHV) causes Kaposi's sarcoma, a cancer particularly prevalent in Africa. In cancer cells, the virus persists in a quiescent form called latency, in which only...
7.
Banerjee S, Smith C, Geballe A, Rothenburg S, Kitzman J, Brennan G
Virus Evol
. 2022 Dec;
8(2):veac105.
PMID: 36483110
Cross-species spillover events are responsible for many of the pandemics in human history including COVID-19; however, the evolutionary mechanisms that enable these events are poorly understood. We have previously modeled...
8.
Bottorff T, Park H, Geballe A, Subramaniam A
PLoS Genet
. 2022 Oct;
18(10):e1010460.
PMID: 36315596
Upstream open reading frames (uORFs) are present in over half of all human mRNAs. uORFs can potently regulate the translation of downstream open reading frames through several mechanisms: siphoning away...
9.
Olson A, Child S, Geballe A
Pathogens
. 2022 Jul;
11(7).
PMID: 35890034
Decades of research on vaccinia virus (VACV) have provided a wealth of insights and tools that have proven to be invaluable in a broad range of studies of molecular virology...
10.
Schleiss M, Fernandez-Alarcon C, Hernandez-Alvarado N, Wang J, Geballe A, McVoy M
Viruses
. 2021 Dec;
13(12).
PMID: 34960639
The development of a vaccine against congenital human cytomegalovirus (HCMV) infection is a major priority. The pentameric complex (PC) of virion envelope proteins gH, gL, UL128, UL130, and UL131A is...