Adam Hotchkiss
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Explore the profile of Adam Hotchkiss including associated specialties, affiliations and a list of published articles.
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10
Citations
92
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Recent Articles
1.
Govindapillai A, Hotchkiss A, Baguma-Nibasheka M, Rose R, Miquerol L, Smithies O, et al.
Sci Rep
. 2018 May;
8(1):6939.
PMID: 29720615
Patients born with congenital heart defects frequently encounter arrhythmias due to defects in the ventricular conduction system (VCS) development. Although recent studies identified transcriptional networks essential for the heart development,...
2.
Feridooni T, Hotchkiss A, Baguma-Nibasheka M, Zhang F, Allen B, Chinni S, et al.
Am J Physiol Heart Circ Physiol
. 2017 Mar;
312(5):H919-H931.
PMID: 28283550
β-Adrenergic receptors (β-ARs) and catecholamines are present in rodents as early as embryonic day (E)10.5. However, it is not known whether β-AR signaling plays any role in the proliferation and...
3.
Egom E, Feridooni T, Hotchkiss A, Kruzliak P, Pasumarthi K
Can J Physiol Pharmacol
. 2015 Apr;
93(6):399-403.
PMID: 25881664
The B-type natriuretic peptide (BNP), a member of the family of vasoactive peptides, is a potent natriuretic, diuretic, and vasodilatory peptide that contributes to blood pressure and volume homeostasis. These...
4.
Lee J, Shahidullah M, Hotchkiss A, Coca-Prados M, Delamere N, Pelis R
Mol Pharmacol
. 2015 Feb;
87(4):697-705.
PMID: 25661037
The purpose of this study was to determine the direction of organic anion (OA) transport across the ciliary body and the transport proteins that may contribute. Transport of several OAs...
5.
Hotchkiss A, Feridooni T, Baguma-Nibasheka M, McNeil K, Chinni S, Pasumarthi K
Am J Physiol Cell Physiol
. 2015 Jan;
308(7):C557-69.
PMID: 25631869
The biological effects of atrial natriuretic peptide (ANP) are mediated by natriuretic peptide receptors (NPRs), which can either activate guanylyl cyclase (NPRA and NPRB) or inhibit adenylyl cyclase (NPRC) to...
6.
Zhang F, Feridooni T, Hotchkiss A, Pasumarthi K
Am J Physiol Cell Physiol
. 2014 Nov;
308(3):C220-8.
PMID: 25411333
Cardiac progenitor cells (CPCs) in the primary and secondary heart fields contribute to the formation of all major cell types in the mammalian heart. While some CPCs remain undifferentiated in...
7.
Hotchkiss A, Feridooni T, Zhang F, Pasumarthi K
Cell Calcium
. 2014 Apr;
55(5):238-51.
PMID: 24680380
Cardiogenesis depends on a tightly regulated balance between proliferation and differentiation of cardiac progenitor cells (CPCs) and their cardiomyocyte descendants. While exposure of early mouse embryos to Ca(2+) channel antagonists...
8.
Hotchkiss A, Robinson J, MacLean J, Feridooni T, Wafa K, Pasumarthi K
Can J Physiol Pharmacol
. 2012 Aug;
90(9):1197-207.
PMID: 22900666
A defining feature of embryonic cardiomyocytes is their relatively high rates of proliferation. A gradual reduction in proliferative capacity throughout development culminates in permanent cell cycle exit by the vast...
9.
Feridooni T, Hotchkiss A, Remley-Carr S, Saga Y, Pasumarthi K
PLoS One
. 2011 Aug;
6(7):e22801.
PMID: 21829519
Doxorubicin (Dox) is an anthracycline used to effectively treat several forms of cancer. Unfortunately, the use of Dox is limited due to its association with cardiovascular complications which are manifested...
10.
McMullen N, Zhang F, Hotchkiss A, Bretzner F, Wilson J, Ma H, et al.
Dev Dyn
. 2009 Oct;
238(11):2787-99.
PMID: 19842178
There is scant information on the fate of cardiac progenitor cells (CPC) in the embryonic heart after chamber specification. Here we simultaneously tracked three lineage-specific markers (Nkx2.5, MLC2v, and ANF)...