Adam Fearnow
Overview
Explore the profile of Adam Fearnow including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
5
Citations
172
Followers
0
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Recent Articles
1.
Christodoulou I, Ho W, Marple A, Ravich J, Tam A, Rahnama R, et al.
J Immunother Cancer
. 2021 Dec;
9(12).
PMID: 34896980
Background: The prognosis of patients with recurrent/refractory acute myelogenous leukemia (AML) remains poor and cell-based immunotherapies hold promise to improve outcomes. Natural Killer (NK) cells can elicit an antileukemic response...
2.
Kristian T, Karimi A, Fearnow A, Waddell J, McKenna M
Cells
. 2021 Sep;
10(9).
PMID: 34571997
Acetylation is a post-translational modification that regulates the activity of enzymes fundamentally involved in cellular and mitochondrial bioenergetic metabolism. NAD dependent deacetylase sirtuin 3 (SIRT3) is localized to mitochondria where...
3.
Klimova N, Fearnow A, Kristian T
Brain Sci
. 2020 Jul;
10(7).
PMID: 32674501
It is commonly accepted that mitochondria represent a major source of free radicals following acute brain injury or during the progression of neurodegenerative diseases. The levels of reactive oxygen species...
4.
Klimova N, Fearnow A, Long A, Kristian T
Exp Neurol
. 2019 Dec;
325:113144.
PMID: 31837320
Global cerebral ischemia depletes brain tissue NAD, an essential cofactor for mitochondrial and cellular metabolism, leading to bioenergetics failure and cell death. The post-ischemic NAD levels can be replenished by...
5.
Leung W, Shaffer C, Reed L, Smith S, Barshop W, Dirkes W, et al.
G3 (Bethesda)
. 2015 Mar;
5(5):719-40.
PMID: 25740935
The Muller F element (4.2 Mb, ~80 protein-coding genes) is an unusual autosome of Drosophila melanogaster; it is mostly heterochromatic with a low recombination rate. To investigate how these properties...