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Adam Cliffe

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Articles 13
Citations 609
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Recent Articles
1.
Cliffe A, Hassan W, Ward D, Elgara M
BMJ Case Rep . 2022 Feb; 15(2). PMID: 35135804
We describe the presentation of a 72-year-old woman with concurrent diagnoses of lung adenocarcinoma in conjunction with disseminated A infection; a rare pathogen which can mimic lung cancer both symptomatically...
2.
Cliffe A, Doupe D, Sung H, Lim I, Ong K, Cheng L, et al.
Nat Commun . 2017 Apr; 8:14905. PMID: 28374738
Understanding the mechanisms of collective cell migration is crucial for cancer metastasis, wound healing and many developmental processes. Imaging a migrating cluster in vivo is feasible, but the quantification of...
3.
Rajendran R, Huang W, Tang A, Liang J, Choo S, Reese T, et al.
Cancer Med . 2014 Jan; 3(1):47-60. PMID: 24403176
Angiogenesis plays a major role in tumor growth and metastasis, with tumor perfusion regarded as a marker for angiogenesis. To evaluate antiangiogenic treatment response in vivo, we investigated arterial spin...
4.
Yang N, Inaki M, Cliffe A, Rorth P
PLoS One . 2012 Jul; 7(7):e40632. PMID: 22808215
The environment through which cells migrate in vivo differs considerably from the in vitro environment where cell migration is often studied. In vivo many cells migrate in crowded and complex...
5.
Inaki M, Vishnu S, Cliffe A, Rorth P
Proc Natl Acad Sci U S A . 2012 Feb; 109(6):2027-32. PMID: 22308382
Directed cell migration is important for normal animal development and physiology. The process can also be subverted by tumor cells to invade other tissues and to metastasize. Some cells, such...
6.
Poukkula M, Cliffe A, Changede R, Rorth P
J Cell Biol . 2011 Feb; 192(3):513-24. PMID: 21300853
Border cells perform a collective, invasive, and directed migration during Drosophila melanogaster oogenesis. Two receptor tyrosine kinases (RTKs), the platelet-derived growth factor/vascular endothelial growth factor-related receptor (PVR) and the epidermal...
7.
Weng R, Chen Y, Bushati N, Cliffe A, Cohen S
Genetics . 2009 Jul; 183(1):399-402. PMID: 19564483
A series of vectors has been designed to enhance the versatility of targeted homologous recombination. Recombinase-mediated cassette exchange permits sequential targeting at any locus and improves flexibility in making user-defined...
8.
Bianco A, Poukkula M, Cliffe A, Mathieu J, Luque C, Fulga T, et al.
Nature . 2007 Jul; 448(7151):362-5. PMID: 17637670
Although directed migration is a feature of both individual cells and cell groups, guided migration has been studied most extensively for single cells in simple environments. Collective guidance of cell...
9.
Grabher C, Cliffe A, Miura K, Hayflick J, Pepperkok R, Rorth P, et al.
J Leukoc Biol . 2006 Oct; 81(1):263-71. PMID: 17046968
Macrophages detecting and migrating toward sites of injury and infection represent one of the first steps in an immune response. Here we directly image macrophage birth and migration in vivo...
10.
Cliffe A, Mieszczanek J, Bienz M
BMC Cell Biol . 2004 Oct; 5:37. PMID: 15458577
Background: The Adenomatous polyposis coli (APC) tumour suppressor is found in multiple discrete subcellular locations, which may reflect sites of distinct functions. In Drosophila epithelial cells, the predominant APC relative...