Adam C Vana
Overview
Explore the profile of Adam C Vana including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
341
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Recent Articles
1.
Mierzwa A, Zhou Y, Hibbits N, Vana A, Armstrong R
Neurosci Lett
. 2013 May;
548:280-5.
PMID: 23684572
In demyelinating diseases, such as multiple sclerosis, remyelination offers the potential to recover function of viable denuded axons by restoring saltatory conduction and/or protecting from further damage. Mice with genetic...
2.
Vana A, Li S, Ribeiro R, Tchantchou F, Zhang Y
Exp Neurol
. 2011 Jun;
231(1):45-55.
PMID: 21683698
Inhibition of phospholipase A(2) (PLA(2)) has recently been found to attenuate the pathogenesis of experimental autoimmune encephalomyelitis (EAE), a commonly used animal model of multiple sclerosis (MS). However, the protective...
3.
Vana A, Flint N, Harwood N, Le T, Fruttiger M, Armstrong R
J Neuropathol Exp Neurol
. 2007 Nov;
66(11):975-88.
PMID: 17984680
In multiple sclerosis, remyelination becomes limited after repeated or prolonged episodes of demyelination. To test the effect of platelet-derived growth factor-A (PDGF-A) in recovery from chronic demyelination we induced corpus...
4.
Vana A, Lucchinetti C, Le T, Armstrong R
Glia
. 2007 Mar;
55(7):687-97.
PMID: 17330875
Myelin transcription factor 1 (Myt1) is a zinc-finger DNA binding protein that influences developing oligodendrocyte progenitor (OP) cell proliferation, differentiation, and myelin gene transcription in vitro. The potential of Myt1...
5.
Armstrong R, Le T, Flint N, Vana A, Zhou Y
J Neuropathol Exp Neurol
. 2006 May;
65(3):245-56.
PMID: 16651886
In multiple sclerosis lesions, remyelination typically fails with repeated or chronic demyelinating episodes and results in neurologic disability. Acute demyelination models in rodents typically exhibit robust spontaneous remyelination that prevents...
6.
Murtie J, Zhou Y, Le T, Vana A, Armstrong R
Neurobiol Dis
. 2005 Apr;
19(1-2):171-82.
PMID: 15837572
Repair of myelin damage in the adult CNS requires oligodendrocyte progenitor (OP) proliferation and subsequent differentiation into remyelinating oligodendrocytes. Platelet-derived growth factor (PDGF) and fibroblast growth factor-2 (FGF2) have been...
7.
Armstrong R, Le T, Frost E, Borke R, Vana A
J Neurosci
. 2002 Sep;
22(19):8574-85.
PMID: 12351731
This study takes advantage of fibroblast growth factor 2 (FGF2) knock-out mice to determine the contribution of FGF2 to the regeneration of oligodendrocytes in the adult CNS. The role of...