Adam A Dowle
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Explore the profile of Adam A Dowle including associated specialties, affiliations and a list of published articles.
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31
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888
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Recent Articles
1.
Perrin A, Dowson M, Davis K, Nam O, Dowle A, Calder G, et al.
Sci Adv
. 2025 Feb;
11(6):eadp6599.
PMID: 39919180
Despite their importance to aquatic ecosystems, global carbon cycling, and sustainable bioindustries, the genomes of photosynthetic bacteria contain large numbers of uncharacterized genes. Here, we develop high-throughput endogenous fluorescent protein...
2.
Dedman C, Chauhan N, Gonzalez-Lanchas A, Baldreki C, Dowle A, Larson T, et al.
Sci Rep
. 2024 Dec;
14(1):31821.
PMID: 39738514
Coccolithophores comprise a major component of the oceanic carbon cycle. These unicellular algae produce ornate structures made of calcium carbonate, termed coccoliths, representing ~ 50% of calcite production in the...
3.
Beck D, Cao H, Tian F, Huang Y, Jiang M, Zhao H, et al.
Nat Commun
. 2024 Nov;
15(1):9697.
PMID: 39516193
The epigenetic landscape plays a critical role in cancer progression, yet its therapeutic potential remains underexplored. Glucocorticoids are essential components of treatments for lymphoid cancers, but resistance, driven in part...
4.
Ma Z, Mondor M, Dowle A, Goycoolea F, Hernandez-Alvarez A
Food Chem
. 2024 Nov;
464(Pt 2):141757.
PMID: 39503093
Biophysical methods such as circular dichroism (CD) and differential scanning calorimetry (DSC) have been minimally used to characterize insect-derived proteins. This study examines the insect Alphitobius diaperinus as a potential...
5.
Chauhan N, Dedman C, Baldreki C, Dowle A, Larson T, Rickaby R
Mar Pollut Bull
. 2024 Oct;
209(Pt A):117136.
PMID: 39427478
Molecular mechanisms driving species-specific environmental sensitivity in coccolithophores are unclear but crucial in understanding species selection and adaptation to environmental change. This study examined proteomic and physiological changes in three...
6.
Eljounaidi K, Radzikowska B, Whitehead C, Taylor D, Conde S, Davis W, et al.
New Phytol
. 2024 May;
243(1):299-313.
PMID: 38757546
Daphniphyllum macropodum produces alkaloids that are structurally complex with polycyclic, stereochemically rich carbon skeletons. Understanding how these compounds are formed by the plant may enable exploration of their biological function...
7.
Burge R, Jameson K, Geoghegan V, Dowle A, Mottram J, Wilkinson A
Mol Biochem Parasitol
. 2024 Mar;
258:111619.
PMID: 38556171
In eukaryotic cells, molecular fate and cellular responses are shaped by multicomponent enzyme systems which reversibly attach ubiquitin and ubiquitin-like modifiers to target proteins. The extent of the ubiquitin proteasome...
8.
Ackroyd B, Dodson E, Mehboob J, Dowle A, Thomas G, Wilkinson A
Microbiology (Reading)
. 2024 Feb;
170(2).
PMID: 38334478
YejABEF is an ATP-binding cassette transporter that is implicated in the sensitivity of to anti-microbial peptides, the best-characterized example being microcin C, a peptide-nucleotide antibiotic that targets aspartyl-tRNA synthetase. Here...
9.
Pesante G, Sabbadin F, Elias L, Steele-King C, Shipway J, Dowle A, et al.
BMC Biol
. 2021 Nov;
19(1):233.
PMID: 34724941
Background: Shipworms are marine xylophagus bivalve molluscs, which can live on a diet solely of wood due to their ability to produce plant cell wall-degrading enzymes. Bacterial carbohydrate-active enzymes (CAZymes),...
10.
Oates N, Abood A, Schirmacher A, Alessi A, Bird S, Bennett J, et al.
Proc Natl Acad Sci U S A
. 2021 Apr;
118(18).
PMID: 33903229
Lignocellulose, the structural component of plant cells, is a major agricultural byproduct and the most abundant terrestrial source of biopolymers on Earth. The complex and insoluble nature of lignocellulose limits...